UniProt Accession

 E7EWX6_HUMAN; E7EWX6 

Genbank Protein ID

 AC011455 

Genbank Nucleotide ID

  

Protein Name

 NAD-dependent protein deacetylase sirtuin-2 

Protein Synonyms/Alias

  

Gene Name

 SIRT2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
175	PLSWMKEKIFSEVTP	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 237 AA 

Protein Sequence

Gene Ontology

 GO:0070403; F:NAD+ binding; IEA:InterPro.
 GO:0016575; P:histone deacetylation; IEA:Compara.
 GO:0090042; P:tubulin deacetylation; IEA:Compara. 

Interpro

 IPR003000; Sirtuin.
 IPR026591; Sirtuin_cat_small_dom.
 IPR026590; Ssirtuin_cat_dom. 

Pfam

 PF02146; SIR2 

SMART

  

PROSITE

 PS50305; SIRTUIN 

PRINTS