CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024263
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative thiosulfate sulfurtransferase 
Protein Synonyms/Alias
 Rhodanese-like protein 
Gene Name
 MSMEG_5789, MSMEI_5636 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
NCBI Taxa ID
 246196 
Lysine Modification
Position
Peptide
Type
References
67VDAQQFSKLLSERGIpupylation[1, 2]
Reference
 [1] Expansion of the mycobacterial "PUPylome".
 Watrous J, Burns K, Liu WT, Patel A, Hook V, Bafna V, Barry CE 3rd, Bark S, Dorrestein PC.
 Mol Biosyst. 2010 Feb;6(2):376-85. [PMID: 20094657]
 [2] Proteome-wide identification of mycobacterial pupylation targets.
 Poulsen C, Akhter Y, Jeon AH, Schmitt-Ulms G, Meyer HE, Stefanski A, Stühler K, Wilmanns M, Song YH.
 Mol Syst Biol. 2010 Jul 13;6:386. [PMID: 20631680
Functional Description
 May be a sulfotransferase involved in the formation of thiosulfate (By similarity). 
Sequence Annotation
 DOMAIN 18 125 Rhodanese 1.
 DOMAIN 154 274 Rhodanese 2.
 ACT_SITE 233 233 Cysteine persulfide intermediate (By
 BINDING 238 238 Substrate (By similarity).
 CROSSLNK 67 67 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 Complete proteome; Isopeptide bond; Reference proteome; Repeat; Transferase; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 277 AA 
Protein Sequence
MARSDVLVST DWAESNLKAP KTVFVEVDED TSAYDTGHIE GAVKLDWKTD LQDPIRRDFV 60
DAQQFSKLLS ERGIANDDTV ILYGGNNNWF AAYAYWYFKL YGHQDVKLLD GGRKKWELDA 120
RPLSAEKVER PQTSYTAKEP DNSIRAFRDE VIAAIGTKNL VDVRSPDEFS GKILAPAHLP 180
QEQSQRPGHI PGAINVPWSK AANEDGTFKS DEELAKLYAE AGLDGEKETI AYCRIGERSS 240
HTWFVLQELL GHKNVKNYDG SWTEYGSLVG APIELGS 277 
Gene Ontology
 GO:0004792; F:thiosulfate sulfurtransferase activity; IEA:EC. 
Interpro
 IPR001763; Rhodanese-like_dom.
 IPR001307; Thiosulphate_STrfase_CS. 
Pfam
 PF00581; Rhodanese 
SMART
 SM00450; RHOD 
PROSITE
 PS00380; RHODANESE_1
 PS00683; RHODANESE_2
 PS50206; RHODANESE_3 
PRINTS