Tag | Content |
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CPLM ID | CPLM-015715 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Proteasomal ubiquitin receptor ADRM1 homolog |
Protein Synonyms/Alias | p42E |
Gene Name | CG13349 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
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211 | RTPSAPSKSGSSRSS | acetylation | [1] |
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Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | May function as a proteasomal ubiquitin receptor. May promote the deubiquitinating activity associated with the 26S proteasome (By similarity). |
Sequence Annotation | DOMAIN 16 124 PH. MOD_RES 6 6 Phosphoserine. MOD_RES 185 185 Phosphoserine. MOD_RES 196 196 Phosphothreonine. MOD_RES 205 205 Phosphothreonine. MOD_RES 207 207 Phosphoserine. MOD_RES 217 217 Phosphoserine. MOD_RES 218 218 Phosphoserine. MOD_RES 219 219 Phosphoserine. MOD_RES 367 367 Phosphothreonine. |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Proteasome; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 389 AA |
Protein Sequence | MFGRQSGLGS SSNSSNLVEF RAGRMNMVGK MVHPDPRKGL VYMTQSDDGL MHFCWKDRTS 60 GKVEDDLIVF PDDFEYKRVD QCKTGRVYVL KFKSSTRRMF FWMQEPKTDK DDEQCRRINE 120 LLNNPPSAHQ RGGGGSNDGD LQYMLNNMSQ QQLMQLFGGV GQMGGLSSLL GQMNSRTPSS 180 RNTSSSGGGG ASALQTPENV SVPRTPSAPS KSGSSRSSSN VNSQVGEGAG SSVDADAPGR 240 SLNIDLSTAL PGADAINQII ADPEHVKTLI VHLPESEDVD DDRKQQIKDN ITSPQFQQAL 300 AQFSSALQSA QLGPVIKQFE LSNEAVAAAF SGNLEDFVRA LEKSLPPGAT MGGKPSASEK 360 KASDPETPTS VARDENTDPA TEKQEEKQK 389 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0005838; C:proteasome regulatory particle; IDA:FlyBase. GO:0061133; F:endopeptidase activator activity; ISS:UniProtKB. GO:0046331; P:lateral inhibition; IMP:FlyBase. GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IC:FlyBase. GO:0043248; P:proteasome assembly; ISS:UniProtKB. |
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