CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017228
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ketosamine-3-kinase 
Protein Synonyms/Alias
 Fructosamine-3-kinase-related protein 
Gene Name
 Fn3krp 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
123RLGERLLKEAGTVGKubiquitination[1]
183QMDMVEKKSGDREALubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein- bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation. 
Sequence Annotation
 MOD_RES 20 20 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Kinase; Phosphoprotein; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 309 AA 
Protein Sequence
METLLKRELG CSSVKATGHS GGGCISQGQS YDTDKGRVFV KVNSKAEARR MFEGEMASLT 60
AILKTGTVKV PKPIKVVDAP GGGSMLVMEH LDMRYLSSHA TKLGTQLADL HLENKRLGER 120
LLKEAGTVGK GGEQAERQYV DQFGFDVVTC CGYLPQVNDW QKNWVEFYAR QRIQPQMDMV 180
EKKSGDREAL ELWSALQLKI PDLFRDLEIV PALLHGDLWG GNVAEDSSGP IIFDPASFYG 240
HSEYELAIAG MFGGFSSSFY SAYHSKIPKT PGFEKRLQLY QLFHYLNHWN HFGSGYRGSS 300
LNIMRNLSK 309 
Gene Ontology
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW. 
Interpro
 IPR016477; Fructo-/Ketosamine-3-kinase.
 IPR011009; Kinase-like_dom. 
Pfam
 PF03881; Fructosamin_kin 
SMART
  
PROSITE
  
PRINTS