CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027109
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Inhibitor of kappaB kinase gamma 
Protein Synonyms/Alias
 NF-kappa-B essential modulator 
Gene Name
 Ikbkg 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
288AEEALVAKQELIDKLubiquitination[1]
296QELIDKLKEEAEQHKubiquitination[1]
320KAQADIYKADFQAERubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kinase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 430 AA 
Protein Sequence
MYIRYCCDDQ DTQTLSCWMN KHPWKNQLSE MVQPSGGPAE DQDMLGEESS LGKPAMLHLP 60
SEQGTPETLQ RCLEENQELR DAIRQSNQML RERCEELLHF QVSQREEKEF LMCKFQEARK 120
LVERLSLEKL DLRSQREQAL KELEQLKKCQ QQMAEDKASV KAQVTSLLGE LQESQSRLEA 180
ATKDRQALEG RIRAVSEQVR QLESEREVLQ QQHSVQVDQL RMQNQSVEAA LRMERQAASE 240
EKRKLAQLQA AYHQLFQDYD SHIKSSKGMQ LEDLRQQLQQ AEEALVAKQE LIDKLKEEAE 300
QHKIVMETVP VLKAQADIYK ADFQAERHAR EKLVEKKEYL QEQLEQLQRE FNKLKVGCHE 360
SARIEDMRKR HVETPQPPLL PAPAHHSFHL ALSNQRRSPP EEPPDFCCPK CQYQAPDMDT 420
LQIHVMECIE 430 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IDA:MGI.
 GO:0001782; P:B cell homeostasis; IMP:MGI.
 GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Compara.
 GO:0006974; P:response to DNA damage stimulus; IEA:Compara. 
Interpro
 IPR021063; NEMO_N. 
Pfam
 PF11577; NEMO 
SMART
  
PROSITE
  
PRINTS