| Tag | Content |
|---|
| CPLM ID | CPLM-006753 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Calponin-3 |
Protein Synonyms/Alias | Calponin, acidic isoform; Calponin, non-muscle isoform |
Gene Name | Cnn3 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 6 | **MTHFNKGPSYGLS | acetylation | [1] | | 156 | TRRFDEGKLKAGQSV | acetylation | [1] | | 197 | DPKMQTDKPFDQTTI | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. |
Sequence Annotation | DOMAIN 26 129 CH.
REPEAT 164 189 Calponin-like 1.
REPEAT 204 229 Calponin-like 2.
REPEAT 243 268 Calponin-like 3. |
Keyword | Actin-binding; Calmodulin-binding; Complete proteome; Direct protein sequencing; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 330 AA |
Protein Sequence | MTHFNKGPSY GLSAEVKNKI ASKYDQQAEE DLRNWIEEVT GMGIGTNFQL GLKDGIILCE 60
LINKLQPGSV KKVNESSLNW PQLENIGNFI KAIQAYGMKP HDIFEANDLF ENGNMTQVQT 120
TLVALAGLAK TKGFHTTIDI GVKYAEKQTR RFDEGKLKAG QSVIGLQMGT NKCASQAGMT 180
AYGTRRHLYD PKMQTDKPFD QTTISLQMGT NKGASQAGMS APGTRRDIYD QKLTLQPVDN 240
STISLQMGTN KVASQKGMSV YGLGRQVYDP KYCAAPTEPV IHNGSQGTGT NGSEISDSDY 300
QAEYPDEYHG EYPDEYPREY QYGDDQGIDY 330 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |