CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030495
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Integrator complex subunit 6 
Protein Synonyms/Alias
 Integrator complex subunit 6, isoform CRA_b; cDNA FLJ39377 fis, clone PERIC2000180, highly similar to Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26 (DDX26), mRNA; cDNA FLJ45485 fis, clone BRTHA2002661, highly similar to Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26 (DDX26), mRNA; cDNA FLJ90465 fis, clone NT2RP3002286, highly similar to Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26 (DDX26), mRNA 
Gene Name
 INTS6 
Gene Synonyms/Alias
 hCG_29123 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
307VVQETGIKVRSRSHGubiquitination[1]
321GLSMAYRKDFQQLLQubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 709 AA 
Protein Sequence
MSVESEQLTG VPLDDSAITP MCEVTGGRSY SVCSPRMLNQ CLESLVQKVQ SGVVINFEKA 60
GPDPSPVEDG QPDISRPFGS QPWHSCHKLI YVRPNPKTGV PIGHWPVPES FWPDQNSPTL 120
PPRTSHPVVK FSCTDCEPMV IDKLPFDKYE LEPSPLTQFI LERKSPQTCW QVYVSNSAKY 180
SELGHPFGYL KASTALNCVN LFVMPYNYPV LLPLLDDLFK VHKAKPTLKW RQSFESYLKT 240
MPPYYLGPLK KAVRMMGAPN LIADSMEYGL SYSVISYLKK LSQQAKIESD RVIGSVGKKV 300
VQETGIKVRS RSHGLSMAYR KDFQQLLQGI SEDVPHRLLD LNMKEYTGFQ VALLNKDLKP 360
QTFRNAYDIP RRNLLDHLTR MRSNLLKSTR RFLKGQDEDQ VHSVPIAQMG NYQEYLKQVP 420
SPLRELDPDQ PRRLHTFGNP FKLDKKGMMI DEADEFVAGP QNKHKRPGEP NMQGIPKRRR 480
CMSPLLRGRQ QNPVVNNHIG GKGPPAPTTQ AQPDLIKPLP LHKISETTND SIIHDVVENH 540
VADQLSSDIT PNAMDTEFSA SSPASLLERP TNHMEALGHD HLGTNDLTVG GFLENHEEPR 600
DKEQCAEENI PASSLNKGKK LMHCRSHEEV NTELKAQIMK EIRKPGRKYE RIFTLLKHVQ 660
GSLQTRLIFL QNVIKEASRF KKRMLIEQLE NFLDEIHRRA NQINHINSN 709 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS