CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040010
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Integrin beta 
Protein Synonyms/Alias
  
Gene Name
 ITGB7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
165MDLSYSMKDDLERVRubiquitination[1]
199GFGSFVDKTVLPFVSubiquitination[1]
211FVSTVPSKLRHPCPTubiquitination[1]
299FHTAGDGKLGGIFMPubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Cell adhesion; Complete proteome; Integrin; Membrane; Reference proteome; Transmembrane. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 471 AA 
Protein Sequence
MVALPMVLVL LLVLSRGESE LDAKIPSTGD ATEWRNPHLS MLGSCQPAPS CQKCILSHPS 60
CAWCKQLNFT ASGEAEARRC ARREELLARG CPLEELEEPR GQQEVLQDQP LSQGARGEGA 120
TQLAPQRVRV TLRPGEPQQL QVRFLRAEGY PVDLYYLMDL SYSMKDDLER VRQLGHALLV 180
RLQEVTHSVR IGFGSFVDKT VLPFVSTVPS KLRHPCPTRL ERCQSPFSFH HVLSLTGDAQ 240
AFEREVGRQS VSGNLDSPEG GFDAILQAAL CQEQIGWRNV SRLLVFTSDD TFHTAGDGKL 300
GGIFMPSDGH CHLDSNGLYS RSTEFDYPSV GQVAQALSAA NIQPIFAVTS AALPVYQELS 360
KLIPKSAVGE LSEDSSNVVQ LIMDAYNSLS STVTLEHSSL PPGVHISYES QCEGPEKREG 420
KAEDRGQCNH VRINQTGLCR VWGLQDWPTG HQLQYSLCPY QCDPGLGPYL G 471 
Gene Ontology
 GO:0008305; C:integrin complex; IEA:InterPro.
 GO:0004872; F:receptor activity; IEA:InterPro.
 GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
 GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:InterPro. 
Interpro
 IPR015812; Integrin_bsu.
 IPR015437; Integrin_bsu-7.
 IPR002369; Integrin_bsu_N.
 IPR003659; Plexin-like.
 IPR016201; Plexin-like_fold.
 IPR002035; VWF_A. 
Pfam
 PF00362; Integrin_beta 
SMART
 SM00187; INB
 SM00423; PSI
 SM00327; VWA 
PROSITE
  
PRINTS
 PR01186; INTEGRINB.