| Tag | Content |
|---|
| CPLM ID | CPLM-007782 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | HTH-type transcriptional regulator HexR |
Protein Synonyms/Alias | Hex regulon repressor |
Gene Name | hexR |
Gene Synonyms/Alias | yebK; b1853; JW1842 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 16 | SQLEHLSKSERKVAE | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Represses the expression of the hex regulon (zwf, eda, glp and gap) (By similarity). |
Sequence Annotation | DOMAIN 1 77 HTH rpiR-type.
DOMAIN 121 260 SIS.
DNA_BIND 37 56 H-T-H motif (Potential). |
Keyword | Complete proteome; DNA-binding; Reference proteome; Repressor; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 289 AA |
Protein Sequence | MNMLEKIQSQ LEHLSKSERK VAEVILASPD NAIHSSIAAM ALEANVSEPT VNRFCRSMDT 60
RGFPDFKLHL AQSLANGTPY VNRNVNEDDS VESYTGKIFE SAMATLDHVR HSLDKSAINR 120
AVDLLTQAKK IAFFGLGSSA AVAHDAMNKF FRFNVPVVYS DDIVLQRMSC MNCSDGDVVV 180
LISHTGRTKN LVELAQLARE NDAMVIALTS AGTPLAREAT LAITLDVPED TDIYMPMVSR 240
LAQLTVIDVL ATGFTLRRGA KFRDNLKRVK EALKESRFDK QLLNLSDDR 289 |
Gene Ontology | GO:0030246; F:carbohydrate binding; IEA:InterPro. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. GO:0006974; P:response to DNA damage stimulus; IEP:EcoliWiki. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |