CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006253
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein SMY2 
Protein Synonyms/Alias
 Suppressor of MYO2-66 protein 
Gene Name
 SMY2 
Gene Synonyms/Alias
 YBR172C; YBR1233 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
102ASPFSSMKEPFIPQSubiquitination[1]
269ELMTKLEKYDTDPFTubiquitination[1]
447QTQTEGFKTSKDLPSubiquitination[1]
450TEGFKTSKDLPSLNSubiquitination[1]
468NPAPWASKVKVNNAIubiquitination[1]
519SVLNWANKSSLPSNQubiquitination[1]
531SNQTIDIKSQFQKSPubiquitination[1]
536DIKSQFQKSPKGMKEubiquitination[1]
565EQKKLWEKVQSSSKQubiquitination[1]
574QSSSKQVKSTSSASTubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Suppressor of the MYO2 gene. 
Sequence Annotation
 DOMAIN 205 261 GYF.
 MOD_RES 12 12 Phosphoserine.
 MOD_RES 96 96 Phosphoserine.
 MOD_RES 129 129 Phosphothreonine.
 MOD_RES 311 311 Phosphothreonine.
 MOD_RES 545 545 Phosphoserine.
 MOD_RES 602 602 Phosphoserine.  
Keyword
 3D-structure; Coiled coil; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 740 AA 
Protein Sequence
MIAPDSQRLF GSFDEQFKDL KLDSVDTENN NTHGVSTILD SSPASVNNNT NGAVAASVNT 60
VPGSTFRSNT PLLGGRHPLS RTSSLIDSIG IQRAASPFSS MKEPFIPQSS GVMSSSFWHG 120
DHPESRVSTP VQQHPLLQRN ESSSSFSYAA NLGVNLSTHS LAVDITPLST PTAAQSHVNL 180
FPSSDIPPNM SMNGMSQLPA PVSVESSWRY IDTQGQIHGP FTTQMMSQWY IGGYFASTLQ 240
ISRLGSTPET LGINDIFITL GELMTKLEKY DTDPFTTFDK LHVQTTSSDS INLNLAPYAS 300
GVAATGTIKA TENDIFKPLT HDNIWDMDGG TTSKGVDIKL ASATTISQTD ESHKQEYKST 360
TMLEKGKKEK SESVAKALLD EQEKRNRELK RKEEARLSKK QKQKEDDLLK KQKEQKEQKE 420
KEALEAEKQK KSEKTKKDTQ TQTEGFKTSK DLPSLNSSSA NPAPWASKVK VNNAIETSIK 480
NGVSSTGKKK GEPLGLQQRN SKEEKQKEEL KSVLNWANKS SLPSNQTIDI KSQFQKSPKG 540
MKESSPLKEL EDPNFIEEQK KLWEKVQSSS KQVKSTSSAS TTTSSWTTVT SKGKAPIGTV 600
VSPYSKTNTS LNSSLTAKTS TTSTTTTFAS MNNVSPRQEF IKWCKSQMKL NSGITNNNVL 660
ELLLSLPTGP ESKELIQETI YANSDVMDGR RFATEFIKRR VACEKQGDDP LSWNEALALS 720
GNDDDGWEFQ VVSKKKGRKH 740 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.
 GO:0019898; C:extrinsic to membrane; IDA:SGD.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IGI:SGD. 
Interpro
 IPR003169; GYF. 
Pfam
 PF02213; GYF 
SMART
 SM00444; GYF 
PROSITE
 PS50829; GYF 
PRINTS