Tag | Content |
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CPLM ID | CPLM-019420 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Rho-related GTP-binding protein RhoV |
Protein Synonyms/Alias | CDC42-like GTPase 2; GTP-binding protein-like 2; Rho GTPase-like protein ARHV; Wnt-1 responsive Cdc42 homolog 2; WRCH-2 |
Gene Name | RHOV |
Gene Synonyms/Alias | ARHV; WRCH2 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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177 | QAQGLAEKIRACCYL | ubiquitination | [1] | 192 | ECSALTQKNLKEVFD | ubiquitination | [1] | 195 | ALTQKNLKEVFDSAI | ubiquitination | [1] | 209 | ILSAIEHKARLEKKL | ubiquitination | [1] |
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Reference | [1] Global identification of modular cullin-RING ligase substrates. Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ. Cell. 2011 Oct 14;147(2):459-74. [ PMID: 21963094] |
Functional Description | Plays a role in the control of the actin cytoskeleton via activation of the JNK pathway (By similarity). |
Sequence Annotation | NP_BIND 38 45 GTP (By similarity). NP_BIND 85 89 GTP (By similarity). NP_BIND 143 146 GTP (By similarity). LIPID 234 234 S-palmitoyl cysteine (By similarity). |
Keyword | Cell membrane; Complete proteome; Endosome; GTP-binding; Lipoprotein; Magnesium; Membrane; Metal-binding; Nucleotide-binding; Palmitate; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 236 AA |
Protein Sequence | MPPRELSEAE PPPLRAPTPP PRRRSAPPEL GIKCVLVGDG AVGKSSLIVS YTCNGYPARY 60 RPTALDTFSV QVLVDGAPVR IELWDTAGQE DFDRLRSLCY PDTDVFLACF SVVQPSSFQN 120 ITEKWLPEIR THNPQAPVLL VGTQADLRDD VNVLIQLDQG GREGPVPQPQ AQGLAEKIRA 180 CCYLECSALT QKNLKEVFDS AILSAIEHKA RLEKKLNAKG VRTLSRCRWK KFFCFV 236 |
Gene Ontology | GO:0005829; C:cytosol; TAS:Reactome. GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. GO:0005886; C:plasma membrane; TAS:Reactome. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome. GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. |
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