CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043370
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Endonuclease III-like protein 1 
Protein Synonyms/Alias
  
Gene Name
 NTHL1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
63GEGAEPLKVPVWEPQubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 236 AA 
Protein Sequence
XSLGPGAGPR GCREEPGPLR RREAAAEARK SHSPVKRPRK AQRLRVAYEG SDSEKGEGAE 60
PLKVPVWEPQ DWQQQLVNIR AMRNKKDAPV DHLGTEHCYD SSAPPKSKVK YIKQTSAILQ 120
QHYGGDIPAS VAELVALPGV GPKMAHLAMA VAWGTVSGIA AVDTHVHRIA NRLRWTKKAT 180
KSPEETRAAL EEWLPRELWH EINGLLVGFG QQTCLPVHPR CHACLNQALC PAAQGL 236 
Gene Ontology
 GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0004519; F:endonuclease activity; IEA:InterPro.
 GO:0006284; P:base-excision repair; IEA:InterPro. 
Interpro
 IPR011257; DNA_glycosylase.
 IPR004036; Endonuclease-III_CS2.
 IPR003651; Endouclease3_FeS-loop_motif.
 IPR003265; HhH-GPD_domain.
 IPR000445; HhH_motif.
 IPR023170; HTH_base_excis_C. 
Pfam
 PF00633; HHH
 PF00730; HhH-GPD 
SMART
 SM00478; ENDO3c
 SM00525; FES 
PROSITE
 PS01155; ENDONUCLEASE_III_2 
PRINTS