CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028516
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MCG141487 
Protein Synonyms/Alias
 Protein Cyp4a32 
Gene Name
 Cyp4a32 
Gene Synonyms/Alias
 mCG_141487 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
114ILGRSDPKANGIYRLubiquitination[1]
155AFHYDILKPYVKNMAacetylation[2]
155AFHYDILKPYVKNMAubiquitination[1]
204MKCAFSHKGSVQVDGubiquitination[1]
252SSNGRLAKQACQLAHubiquitination[1]
270DGVIKMRKDQLQDEGubiquitination[1]
283EGELENIKKKRRLDFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 509 AA 
Protein Sequence
MSVSALSPTR FADSLSGFLQ VASVLGLLLL LVKAVQFYLH RKWLLKALQQ FPSPPFHWFF 60
GHEQFKGEQE LKEVVSCIEH FPSAFPCWFW GSNAYLTVYD PDYMKVILGR SDPKANGIYR 120
LLAPWIGYGL LLLNGQPWFQ HRRMLTPAFH YDILKPYVKN MADSIRLMLD KWERLAGQDS 180
SIEIFQHISL MTLDTVMKCA FSHKGSVQVD GNYKTYLQAI GDLNNLFHSR VRNIFHQNDT 240
IYRLSSNGRL AKQACQLAHD HTDGVIKMRK DQLQDEGELE NIKKKRRLDF LDILLFARME 300
NGDSMSDKDL RAEVDTFMFE GHDTTASGVS WIFYALATHP EHQQRCREEV QSLLGDGSSI 360
TWDHLDQIPY TTMCIKEALR LYPPVPGIVR ELSTSVTFPD GRSLPKGVQV TLSIYGLHHN 420
PKVWPNPEVF DPSRFAPDSP RHSHSFLPFS GGARNCIGKQ FAMSELKVIV ALTLLHFELL 480
PDPTRVPEPL ARIVLKSKNG IYLHLKKLH 509 
Gene Ontology
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
 GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. 
Interpro
 IPR001128; Cyt_P450.
 IPR017972; Cyt_P450_CS.
 IPR002401; Cyt_P450_E_grp-I. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
 PS00086; CYTOCHROME_P450 
PRINTS
 PR00463; EP450I.
 PR00385; P450.