CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041829
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Inter-alpha trypsin inhibitor, heavy chain 2 
Protein Synonyms/Alias
 Inter-alpha-trypsin inhibitor heavy chain H2 
Gene Name
 Itih2 
Gene Synonyms/Alias
 mCG_5023 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
208KIHLQPGKLAKHLEVubiquitination[1]
256QKAHVSFKPTVAQQRubiquitination[1]
371NDLVSATKTQIADAKubiquitination[1]
383DAKRYIEKIQPSGGTubiquitination[1]
491QDTSSQLKKFYNQVSubiquitination[1]
492DTSSQLKKFYNQVSTubiquitination[1]
609LAPTAAIKRKITKTIubiquitination[1]
752NGQLIGAKRAENGKLubiquitination[1]
758AKRAENGKLSTYFGKubiquitination[1]
838LLHRVWRKHPVNVDFubiquitination[1]
936GFIDGHYKDYFVPQLubiquitination[1]
948PQLYSFLKRP*****ubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 950 AA 
Protein Sequence
MSSKMQRPVC LLIWLFLLEA QAFEIPINGN SEFAEYSDLV ELAPDKLPFV QENGRHQRSL 60
PEESGEETDT VDPVTLYSYK VQSTITSRVA TTTIQSKLVN NSPLPQSVVF DVQIPKGAFI 120
SNFTMTVNGM TFTSSIKEKT VGRALYSQAR AKGKTAGWVR SRTLDMENFN TEVNIPPGAK 180
VQFELHYQEV KWRKLGSYEH KIHLQPGKLA KHLEVNVWII EPQGMRFLHV PDTFEGHFQG 240
VPVISKGQQK AHVSFKPTVA QQRKCPNCTE TAVNGELVVM YDVNREEKAG ELEVFNGYFV 300
HFFAPENLDP IPKNILFVID VSGSMWGIKM KQTVEAMKTI LDDLRTDDQF SVVDFNHNVR 360
TWRNDLVSAT KTQIADAKRY IEKIQPSGGT NINEALLRAI FILNEASNMG LLNPDSVSLI 420
ILVSDGDPTV GELKLSKIQK NVKQSIQDNI SLFSLGIGFD VDYDFLKRLS NENRGIAQRI 480
YGNQDTSSQL KKFYNQVSTP LLRNVQFNYP QASVTDVTQN NFHNYFGGSE IVVAGKFDPS 540
KLTEVQSIIT ATSANTELVL ETLSQMDDLE EFLSKDKHAD PDFTKKLWAY LTINQLLAER 600
SLAPTAAIKR KITKTILQMS LDHHIVTPLT AMVIENDAGD ERMLADSPPQ DHSCCSGALY 660
YGTKVASGPI PSWANPSPTP MSAMLAVGAK PLESTPPTHL NQVENDPHFI IYLPKSKRNI 720
CFNIDSEPGK ILSLVSDPES GIVVNGQLIG AKRAENGKLS TYFGKLGFYF QKEGMKIEIS 780
TETITLSSGS STSRLSWSDT AHLGNSRVLI SVKKEKSVTL TLNKELFFSV LLHRVWRKHP 840
VNVDFLGIYA PPIDKFSPRV HGLLGQFMQE PAIHIFNERP GKEPGKPEAS MEVKGHKLTV 900
TRGLQKDYRT DIVFGTDVPC WFVHNSGKGF IDGHYKDYFV PQLYSFLKRP 950 
Gene Ontology
 GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
 GO:0030212; P:hyaluronan metabolic process; IEA:InterPro. 
Interpro
 IPR010600; ITI_HC_C.
 IPR013694; VIT.
 IPR002035; VWF_A. 
Pfam
 PF06668; ITI_HC_C
 PF08487; VIT
 PF00092; VWA 
SMART
 SM00609; VIT
 SM00327; VWA 
PROSITE
 PS51468; VIT
 PS50234; VWFA 
PRINTS