UniProt Accession

 GBRL1_RAT; Q0VGK0 

Genbank Protein ID

 BC105627 

Genbank Nucleotide ID

 AAI05628.1 

Protein Name

 Gamma-aminobutyric acid receptor-associated protein-like 1 

Protein Synonyms/Alias

 GABA(A) receptor-associated protein-like 1; Glandular epithelial cell protein 1; GEC-1 

Gene Name

 Gabarapl1 

Gene Synonyms/Alias

 Gec1 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
2	******MKFQYKEDH	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity). 

Sequence Annotation

 REGION 1 22 Interaction with beta-tubulin (By
 REGION 36 68 Interaction with GABRG2 (By similarity).
 LIPID 116 116 Phosphatidylethanolamine amidated glycine  

Keyword

 Autophagy; Complete proteome; Cytoplasm; Cytoplasmic vesicle; Cytoskeleton; Endoplasmic reticulum; Golgi apparatus; Lipoprotein; Membrane; Microtubule; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 117 AA 

Protein Sequence

Gene Ontology

 GO:0005776; C:autophagic vacuole; IEA:UniProtKB-SubCell.
 GO:0044297; C:cell body; IDA:RGD.
 GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
 GO:0032839; C:dendrite cytoplasm; IDA:RGD.
 GO:0032590; C:dendrite membrane; IDA:RGD.
 GO:0005783; C:endoplasmic reticulum; IDA:RGD.
 GO:0005794; C:Golgi apparatus; IDA:RGD.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0006914; P:autophagy; IEA:UniProtKB-KW. 

Interpro

 IPR004241; Atg8_ubiquitin-like. 

Pfam

 PF02991; Atg8 

SMART

  

PROSITE

  

PRINTS