CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041902
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 D-tyrosyl-tRNA(Tyr) deacylase 1 
Protein Synonyms/Alias
 Histidyl-tRNA synthetase-like, isoform CRA_a 
Gene Name
 Hars2 
Gene Synonyms/Alias
 Harsl; mCG_124899 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
79VREKILDKIISCFKRacetylation[1]
90CFKRHGAKGLDTPAFacetylation[2]
90CFKRHGAKGLDTPAFsuccinylation[2]
362IKAEMLYKNNPKLLTacetylation[2]
362IKAEMLYKNNPKLLTsuccinylation[2]
366MLYKNNPKLLTQLHYacetylation[2]
366MLYKNNPKLLTQLHYsuccinylation[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; Complete proteome; Ligase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 424 AA 
Protein Sequence
MPHLGPLRRR AWAALLGQLL RPPSTVCTRG CHSQVAKAVL TSEQLKSHQE KPNFVIKVPK 60
GTRDLSPQQM VVREKILDKI ISCFKRHGAK GLDTPAFELK EMLTEKYEDN FGLMYDLKDQ 120
GGELLSLRYD LTVPFARYLA MNKLKKMKRY QVGKVWRRES PAIAQGRYRE FCQCDFDIAG 180
EFDPMIPDAE CLRIMCEILS GLQLGDFLIK VNDRRVVDGI FAVCGVPESK LRTICSSMDK 240
LDKMSWEGVR HEMVAKKGLA PEVADRIGDF VQYHGGISLV EDLFKDPRLS QSQLALQGLG 300
DLKLLFEYLR LFGIADKMSG EKVRTTETQV FVATPQKNFL QERLKIIAEL WDAGIKAEML 360
YKNNPKLLTQ LHYCEKADIP LMVIIGEQER NEGVIKLRSV ASREEVTINR ESLVAEIQKR 420
LSES 424 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0004812; F:aminoacyl-tRNA ligase activity; IEA:UniProtKB-KW. 
Interpro
 IPR004154; Anticodon-bd.
 IPR004516; HisRS/HisZ. 
Pfam
 PF03129; HGTP_anticodon 
SMART
  
PROSITE
  
PRINTS