CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044408
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 F-box only protein 6 
Protein Synonyms/Alias
  
Gene Name
 FBXO6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
54LREGFITKDWDQPVAubiquitination[1]
216SSIVVSPKMTRNQASubiquitination[1]
231SEAQPGQKHGQEEAAubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 249 AA 
Protein Sequence
XNELPENILL ELFTHVPARQ LLLNCRLVCS LWRDLIDLMT LWKRKCLREG FITKDWDQPV 60
ADWKIFYFLR SLHRNLLRNP CAEEDMFAWQ IDFNGGDRWK VESLPGAHGT DFPDPKVKKY 120
FVTSYEFAAR ADCGCTYQLK VQLASADYFV LASFEPPPVT IQQWNNATWT EVSYTFSDYP 180
RGVRYILFQH GGRDTQYWAG WYGPRVTNSS IVVSPKMTRN QASSEAQPGQ KHGQEEAAQS 240
PYRAVVQIF 249 
Gene Ontology
 GO:0030163; P:protein catabolic process; IEA:InterPro. 
Interpro
 IPR007397; F-box-assoc_dom.
 IPR001810; F-box_dom_cyclin-like.
 IPR008979; Galactose-bd-like. 
Pfam
 PF04300; FBA 
SMART
 SM00256; FBOX 
PROSITE
 PS51114; FBA
 PS50181; FBOX 
PRINTS