| Tag | Content |
|---|
| CPLM ID | CPLM-010006 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | PTS system fructose-specific EIIABC component |
Protein Synonyms/Alias | EIIABC-Fru; Fructose-specific phosphotransferase enzyme IIA component; EII-Fru; PTS system fructose-specific EIIA component; Fructose-specific phosphotransferase enzyme IIB component; EIII-Fru; PTS system fructose-specific EIIB component; Fructose permease IIC component; PTS system fructose-specific EIIC component |
Gene Name | fruA |
Gene Synonyms/Alias | MPN_078; MP077 |
Created Date | July 27, 2013 |
Organism | Mycoplasma pneumoniae (strain ATCC 29342 / M129) |
NCBI Taxa ID | 272634 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 27 | KDKTSFLKQACRVLQ | acetylation | [1] |
|
Reference | [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium. van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC. Mol Syst Biol. 2012 Feb 28;8:571. [ PMID: 22373819] |
Functional Description | The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity). |
Sequence Annotation | DOMAIN 4 149 PTS EIIA type-2.
DOMAIN 179 275 PTS EIIB type-2.
DOMAIN 310 687 PTS EIIC type-2.
ACT_SITE 68 68 Tele-phosphohistidine intermediate; for
ACT_SITE 185 185 Phosphocysteine intermediate; for EIIB |
Keyword | Cell membrane; Complete proteome; Kinase; Membrane; Phosphotransferase system; Reference proteome; Sugar transport; Transferase; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 694 AA |
Protein Sequence | MFKPLLSAEL FFNWTAKDFK DKTSFLKQAC RVLQDKNCIK EEQIALTALK EREAQITTGI 60
MSKLALPHMQ SATVLKPFVA VFKVNNVDWQ SLDNQPVKLI FLIGVPKDQG NLHLEFISQF 120
SKLMLQDEFA NKVPNIRSFN GLINLIDSFQ QTAVASQPVV NEAAAQTEEP KDTNTQYDFV 180
AVTACPTGIA HTFMAKEALE KFARDHNLKV KVETQGTDGI QNQLTESDLN NTKGIILACD 240
RLIDLTRFYG HANVVEVSTT KAIKTPQTVY DQVVKKEGKL LGNKSSDSAS QTELKETTEQ 300
LSFKDFHKRI YRAILSGVSY MLPFVVFGGI LIAIAFLIDI NNAGNAGKQF GSKDPIANWF 360
KTLGGLSFGL IVPILSAYIA FALVGRQGLL PGFIVGLISA GKFLLNIDIV TGKIDWATES 420
KVSSGFFGAI FGGLLAAVLI IVQQRYIYRK LPQALQGIKN ILFIPLLGTL VTAALFWVIN 480
IPLIYLNYGL SKFLQIMDKP YLAPLLGLVI GLMMCFDLGG PVNKAAYVFG VVSLESQNSG 540
TVAMASAILS GMVPPLGIAI AATIRKQCFD KEELPAAYAC YVMGLSFISE GAIPFVAKRP 600
KIMLAANLIG GAVCGVLTGA FALTIRAPHG GVFVFALLKT NLEGIAGNTL QIGAGVGLAL 660
LALIVSSFIS AGIIIGHNLL VVRKKTKQLV NTNA 694 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0016301; F:kinase activity; IEA:UniProtKB-KW. GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:EC. GO:0005351; F:sugar:hydrogen symporter activity; IEA:InterPro. GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |