| Tag | Content |
|---|
| CPLM ID | CPLM-015587 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transmembrane protease serine 11F |
Protein Synonyms/Alias | Airway trypsin-like protease 4 |
Gene Name | TMPRSS11F |
Gene Synonyms/Alias | HATL4 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 71 | SFKVTNIKYKENYGI | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Probable serine protease (By similarity). |
Sequence Annotation | DOMAIN 52 178 SEA.
DOMAIN 206 437 Peptidase S1.
ACT_SITE 248 248 Charge relay system (By similarity).
ACT_SITE 293 293 Charge relay system (By similarity).
ACT_SITE 389 389 Charge relay system (By similarity).
DISULFID 233 249 By similarity.
DISULFID 358 374 By similarity.
DISULFID 385 413 By similarity. |
Keyword | Complete proteome; Disulfide bond; Hydrolase; Membrane; Polymorphism; Protease; Reference proteome; Serine protease; Signal-anchor; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 438 AA |
Protein Sequence | MMYAPVEFSE AEFSRAEYQR KQQFWDSVRL ALFTLAIVAI IGIAIGIVTH FVVEDDKSFY 60
YLASFKVTNI KYKENYGIRS SREFIERSHQ IERMMSRIFR HSSVGGRFIK SHVIKLSPDE 120
QGVDILIVLI FRYPSTDSAE QIKKKIEKAL YQSLKTKQLS LTINKPSFRL TPIDSKKMRN 180
LLNSRCGIRM TSSNMPLPAS SSTQRIVQGR ETAMEGEWPW QASLQLIGSG HQCGASLISN 240
TWLLTAAHCF WKNKDPTQWI ATFGATITPP AVKRNVRKII LHENYHRETN ENDIALVQLS 300
TGVEFSNIVQ RVCLPDSSIK LPPKTSVFVT GFGSIVDDGP IQNTLRQARV ETISTDVCNR 360
KDVYDGLITP GMLCAGFMEG KIDACKGDSG GPLVYDNHDI WYIVGIVSWG QSCALPKKPG 420
VYTRVTKYRD WIASKTGM 438 |
Gene Ontology | GO:0005576; C:extracellular region; IEA:InterPro. GO:0005887; C:integral to plasma membrane; IEA:InterPro. GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |