CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-025812
UniProt Accession
Q59ES7_HUMAN
;
Q59ES7
Genbank Protein ID
AB209734
Genbank Nucleotide ID
BAD92971.1
Protein Name
Putative G-protein coupled receptor variant
Protein Synonyms/Alias
Gene Name
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
26
PCPNMYF
K
SDELEFA
ubiquitination
[1]
Reference
[1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
Mol Cell. 2011 Oct 21;44(2):325-40. [
PMID: 21906983
]
Functional Description
Sequence Annotation
Keyword
Developmental protein; G-protein coupled receptor; Membrane; Receptor; Transducer; Transmembrane; Transmembrane helix; Wnt signaling pathway.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
328 AA
Protein Sequence
KTSGGQGYKF LGIDQCAPPC PNMYFKSDEL EFAKSFIGTV SIFCLCATLF TFLTFLIDVR 60
RFRYPERPII YYSVCYSIVS LMYFIGFLLG DSTACNKADE KLELGDTVVL GSQNKACTVL 120
FMLLYFFTMA GTVWWVILTI TWFLAAGRKW SCEAIEQKAV WFHAVAWGTP GFLTVMLLAL 180
NKVEGDNISG VCFVGLYDLD ASRYFVLLPL CLCVFVGLSL LLAGIISLNH VRQVIQHDGR 240
NQEKLKKFMI RIGVFSGLYL VPLVTLLGCY VYEQVNRITW EITWVSDHCR QYHIPCPYQV 300
KAITWIMSLF TFNVENVSWK YTCHGCKS 328
Gene Ontology
GO:0016021
; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004930
; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
GO:0042813
; F:Wnt-activated receptor activity; IEA:InterPro.
GO:0007275
; P:multicellular organismal development; IEA:UniProtKB-KW.
GO:0016055
; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
Interpro
IPR000539
; Frizzled.
IPR015526
; Frizzled/SFRP.
IPR026543
; FZD6.
IPR017981
; GPCR_2-like.
Pfam
PF01534
; Frizzled
SMART
PROSITE
PS50261
; G_PROTEIN_RECEP_F2_4
PRINTS
PR00489
; FRIZZLED.