| Tag | Content |
|---|
| CPLM ID | CPLM-008407 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glypican-4 |
Protein Synonyms/Alias | K-glypican; Secreted glypican-4 |
Gene Name | Gpc4 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 398 | EKLKQAKKFWSSLPS | acetylation | [1] |
|
Reference | [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y. Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [ PMID: 22826441] |
Functional Description | Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system. |
Sequence Annotation | MOD_RES 357 357 Phosphoserine (By similarity).
LIPID 529 529 GPI-anchor amidated serine (Potential).
CARBOHYD 494 494 O-linked (Xyl...) (glycosaminoglycan)
CARBOHYD 498 498 O-linked (Xyl...) (glycosaminoglycan)
CARBOHYD 500 500 O-linked (Xyl...) (glycosaminoglycan)
CARBOHYD 514 514 N-linked (GlcNAc...) (Potential). |
Keyword | Cell membrane; Complete proteome; Glycoprotein; GPI-anchor; Heparan sulfate; Lipoprotein; Membrane; Phosphoprotein; Proteoglycan; Reference proteome; Secreted; Signal. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 557 AA |
Protein Sequence | MARLGLLALL CTLAALSASL LAAELKSKSC SEVRRLYVSK GFNKNDAPLY EINGDHLKIC 60
PQDYTCCSQE MEEKYSLQSK DDFKTVVSEQ CNHLQAIFAS RYKKFDEFFK ELLENAEKSL 120
NDMFVKTYGH LYMQNSELFK DLFVELKRYY VAGNVNLEEM LNDFWARLLE RMFRLVNSQY 180
HFTDEYLECV SKYTEQLKPF GDVPRKLKLQ VTRAFVAART FAQGLAVARD VVSKVSVVNP 240
TAQCTHALLK MIYCSHCRGL VTVKPCYNYC SNIMRGCLAN QGDLDFEWNN FIDAMLMVAE 300
RLEGPFNIES VMDPIDVKIS DAIMNMQDNS VQVSQKVFQG CGPPKPLPAG RISRSISESA 360
FSARFRPYHP EQRPTTAAGT SLDRLVTDVK EKLKQAKKFW SSLPSTVCND ERMAAGNENE 420
DDCWNGKGKS RYLFAVTGNG LANQGNNPEV QVDTSKPDIL ILRQIMALRV MTSKMKNAYN 480
GNDVDFFDIS DESSGEGSGS GCEYQQCPSE FEYNATDHSG KSANEKADSA GGAHAEAKPY 540
LLAALCILFL AVQGEWR 557 |
Gene Ontology | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW. GO:0009897; C:external side of plasma membrane; ISO:MGI. GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell. GO:0005796; C:Golgi lumen; TAS:Reactome. GO:0005578; C:proteinaceous extracellular matrix; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |