| Tag | Content |
|---|
| CPLM ID | CPLM-020457 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein tweety homolog 3 |
Protein Synonyms/Alias | hTTY3 |
Gene Name | TTYH3 |
Gene Synonyms/Alias | KIAA1691 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 476 | YTSSMRAKYLATSQP | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. |
Sequence Annotation | MOD_RES 504 504 Phosphoserine (By similarity).
MOD_RES 522 522 Phosphoserine.
CARBOHYD 126 126 N-linked (GlcNAc...) (Potential).
CARBOHYD 144 144 N-linked (GlcNAc...).
CARBOHYD 351 351 N-linked (GlcNAc...) (Probable). |
Keyword | Alternative splicing; Calcium; Cell membrane; Chloride; Chloride channel; Complete proteome; Glycoprotein; Ion channel; Ion transport; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 523 AA |
Protein Sequence | MAGVSYAAPW WVSLLHRLPH FDLSWEATSS QFRPEDTDYQ QALLLLGAAA LACLALDLLF 60
LLFYSFWLCC RRRKSEEHLD ADCCCTAWCV IIATLVCSAG IAVGFYGNGE TSDGIHRATY 120
SLRHANRTVA GVQDRVWDTA VGLNHTAEPS LQTLERQLAG RPEPLRAVQR LQGLLETLLG 180
YTAAIPFWRN TAVSLEVLAE QVDLYDWYRV CLLGVLALVI SWGALGLELA VSVGSSDFCV 240
DPDAYVTKMV EEYSVLSGDI LQYYLACSPR AANPFQQKLS GSHKALVEMQ DVVAELLRTV 300
PWEQPATKDP LLRVQEVLNG TEVNLQHLTA LVDCRSLHLD YVQALTGFCY DGVEGLIYLA 360
LFSFVTALMF SSIVCSVPHT WQQKRGPDED GEEEAAPGPR QAHDSLYRVH MPSLYSCGSS 420
YGSETSIPAA AHTVSNAPVT EYMSQNANFQ NPRCENTPLI GRESPPPSYT SSMRAKYLAT 480
SQPRPDSSGS H 491 |
Gene Ontology | GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IDA:UniProtKB. GO:0005254; F:chloride channel activity; IMP:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |