CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039362
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Myo7b 
Protein Synonyms/Alias
  
Gene Name
 Myo7b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
1395KATPLEVKEQTVEAAacetylation[1]
1515AMALQDRKATDDVTLacetylation[1]
1526DVTLLPFKKGDLLILacetylation[1]
1755ALLPHAQKFIDSRKKacetylation[1]
1800AAEQNVSKLHHEVYLacetylation[1]
1813YLPNDTNKTLEVSSSacetylation[1]
1904WLNVTPGKDVNADTIacetylation[1]
1977LMSSEEWKKSLLLECacetylation[1]
1996NKSVAEAKVEFLKRIacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2152 AA 
Protein Sequence
MSVFRLGDHV WLDPPSSNKT GVAIGGIVKE TKLGKTLIED DEGKEHWISA EDLSTLRPMH 60
PNSAQGVDDM IRLGDLNEAG VVHNLLIRYQ QHKIYTYTGS ILVAVNPFQM LPLYTLEQVQ 120
IYYSRHMGEL PPHVFAIANS CYFNMKKNKR DQCCIISGES GAGKTETTKL ILQFLATVSG 180
QHSWIEQQVL EANPILEAFG NAKTIRNDNS SRFGKYIDIH FNSSGVIEGA SIEHFLLEKS 240
RVCRQAAEER NYHIFYCMLM GMSLEEKNML GLGMPSEYHY LTMGNCTSYE GLSDAKDYAH 300
VRSAMKILQF SDSENWDISK LLAAILHLGN VGFMAAVFEN LDSSDVMETP AFPFAMKLLE 360
VQHQALRDCL IKHTIPILGE FVSRPLNIAQ AADRRDAFVK GIYGHLFLWI VKKINAAIFT 420
PQAQDPQNVR RAIGLLDIFG FENFQNNSFE QLCINFANEH LQQFFVKHVF TMEQEEYLSE 480
NITWNYIHYT DNQPILDMLA LKPMSIISLL DEESRFPQGT DVTMLQKLNS IHANNKSFLR 540
PKSIHDTRFG IAHFAGDVYY QAEGFLEKNR DVLSTDILIL IHSSKNKFLK EIFNLDLPQT 600
KLGHGTICQV KTKTGGQIFK PSDSTKRSVT LSSQFKQSLE QLMKILTNCQ PYFVRCIKPN 660
EYKKPLLFDR ELCIQQLRYS GMMETVHIRK SGFPIRYTFD EFSQRFRVLL PSPERVQFQN 720
KHRQMTSRIA DLCLGTDKEW KMGKTKIFLK DHQDTMLEIQ RSQALDGAAI RIQRVLRGHK 780
YRKEFLRQKR AAVTLQAVWR GHNQRKNFKL ILMGFERLQA IARSHLLMRQ FQTMRQKIVQ 840
LQARCRGYLV RQQVQAKRRA VVIIQAHARG MVARKSYWQQ KSSGPPVILA KEPKGQGVAL 900
DRKRKSIYDT VTDTAMVEKV FGFLPAMIGG QEGPAPTRFE DLEVKTQKLH EVDLDTVPMT 960
EMPGEDVDGL AEYTFPKFAV TYFQKSASHT HIQKPLRYPL LYHENDTDHS AALAVWIIIL 1020
RFMGDLPEPQ AYGRSSLTGS SVMRQIHDRL DKDSVTQGPQ HNRSTQVASQ QNIGEEVFKF 1080
DGPISDRPMS NLEKVHFIVG YAIMRPGLRD EIYCQICKQL SENYKTSSRA RGWILLSLCL 1140
GCFPPSERFM KYLLNFISQG PASYGPFCAE RLQRTFANGV RAEPPTWLEL QAVKSKKHIP 1200
IQVILATGRS LTISVDSAST SREICQQIAQ KQGLRDKLGF SLQVAVYDKF WSLGNSCDHV 1260
MDAVAQCEQL AWERGESQRQ APWRIYFRKE FFTPWHDSRE DPVSTELIYH QVLRGVWSGE 1320
YNFEKEEDLV ELLARHCYVQ LGATVKSNAV QELLPSCVPS KLYRTKSPEK WASLVIAAHA 1380
KAPYTQSKAT PLEVKEQTVE AARLLWPLLF SRLFEVTTLS GPRLPKTQLI LAINWKGMYF 1440
LDQKERTLLG LSFAEVMGLI ANRDAPGGKS LLLSTLHEEY EFASPSSVAI AEMVALFLAG 1500
LKERSVFAMA LQDRKATDDV TLLPFKKGDL LILTKKQGLL ASENWVLGQN DRTGKTGLVP 1560
TACLYTIPSV TKPSAQLLNL LAMSPEKRKL AAQEVQASEP PLEEQLTELP YTLEEFSYQY 1620
FRAPEKETIS RAAMPMARSR GHLWAYSPEP LRQPLLKSVH DKAKLRDSAC QIFLAILKYT 1680
GDYPSRQSWH SLELTDQMFS LALKEPALQD ELYCQILKQL THNSIRFSEE RAWQLLWLCT 1740
GLFPPGKALL PHAQKFIDSR KKKPLALDCS RRLHRILRVG PRKQPPHHVE VKAAEQNVSK 1800
LHHEVYLPND TNKTLEVSSS SRVRDLCEGI ATRLQLASWD GCSLFIKITD KVISLKEGDF 1860
FFDSLRQVSD WVKKNRPQKE GASTTLPYQV FFMRKLWLNV TPGKDVNADT ILHYHQELPK 1920
YMRGFHKCSR EDAIYLAGLI YKIQFGSDRS QMASVSKILK ELVPQNLTRL MSSEEWKKSL 1980
LLECDKHKNK SVAEAKVEFL KRIYRWPTFG SAFFEVKQTS EPSYPDILLI AINRHGLLLI 2040
HPKTKELLDT FPFTKISSWS SGNTYFHMAL GSLGQGSRLL CETSLGYKMD DLLTSYVQQI 2100
LSAVNKHRGF RAPAPAQPDH ENLWRLPVCP PDRPQGTESP TQACRKCCVL SI 2152 
Gene Ontology
 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003774; F:motor activity; IEA:InterPro. 
Interpro
 IPR019749; Band_41_domain.
 IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
 IPR019748; FERM_central.
 IPR000299; FERM_domain.
 IPR000048; IQ_motif_EF-hand-BS.
 IPR001609; Myosin_head_motor_dom.
 IPR000857; MyTH4_dom.
 IPR027417; P-loop_NTPase.
 IPR011993; PH_like_dom.
 IPR001452; SH3_domain. 
Pfam
 PF00373; FERM_M
 PF00612; IQ
 PF00063; Myosin_head
 PF00784; MyTH4 
SMART
 SM00295; B41
 SM00015; IQ
 SM00242; MYSc
 SM00139; MyTH4
 SM00326; SH3 
PROSITE
 PS50057; FERM_3
 PS50096; IQ
 PS51016; MYTH4
 PS50002; SH3 
PRINTS
 PR00193; MYOSINHEAVY.