UniProt Accession

 TM230_HUMAN; Q96A57; B2RDM8; D3DVZ9; Q0VGC8; Q5TDS5; Q96ES2; Q9P0A7 

Genbank Protein ID

 AF161392; AY359115; AK315606; AL121890; AL121924; AL121890; AL121924; AL121924; AL121890; AL121924; AL121890; CH471133; CH471133; CH471133; CH471133; CH471133; BC070212; BC009768; BC009769; BC009770; BC011990; BC015113; BC110408 

Genbank Nucleotide ID

 AAF28952.1; AAQ89473.1; BAG37975.1; CAI19213.1; CAI19213.1; CAI19216.1; CAI19216.1; CAI22630.1; CAI22630.1; CAI22627.1; CAI22627.1; EAX10431.1; EAX10432.1; EAX10433.1; EAX10434.1; EAX10437.1; AAH70212.1; AAH09768.1; AAH09769.1; AAH09770.1; AAH11990.1; AAH15113.1; AAI10409.2 

Protein Name

 Transmembrane protein 230 

Protein Synonyms/Alias

  

Gene Name

 TMEM230 

Gene Synonyms/Alias

 C20orf30; HSPC274; UNQ2432/PRO4992 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
79	ATGIPSSKVKYSRLS	ubiquitination	[1, 2]
81	GIPSSKVKYSRLSST	ubiquitination	[1]
98	GYIDLQFKKTPPKIP	ubiquitination	[2, 3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

 MOD_RES 23 23 Phosphoserine.
 MOD_RES 24 24 Phosphoserine (By similarity).
 MOD_RES 25 25 Phosphothreonine (By similarity).  

Keyword

 Alternative splicing; Complete proteome; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 120 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 

Interpro

 IPR008590; DUF872_TM. 

Pfam

 PF05915; DUF872 

SMART

  

PROSITE

  

PRINTS