CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019472
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 48 
Protein Synonyms/Alias
 Zinc finger protein 553 
Gene Name
 ZNF48 
Gene Synonyms/Alias
 ZNF553 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
209RQSSDLVKHQRTHTGacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 ZN_FING 112 134 C2H2-type 1.
 ZN_FING 140 162 C2H2-type 2.
 ZN_FING 192 214 C2H2-type 3.
 ZN_FING 220 242 C2H2-type 4.
 ZN_FING 275 297 C2H2-type 5.
 ZN_FING 303 325 C2H2-type 6.
 ZN_FING 331 353 C2H2-type 7.
 ZN_FING 359 381 C2H2-type 8.
 ZN_FING 451 473 C2H2-type 9.
 ZN_FING 479 501 C2H2-type 10.
 ZN_FING 543 565 C2H2-type 11.
 ZN_FING 571 593 C2H2-type 12.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 618 AA 
Protein Sequence
MERAVEPWGP DLHRPEEREP QRGARTGLGS ENVISQPNEF EHTPQEDDLG FKEEDLAPDH 60
EVGNASLKPE GIQNWDDLWV QREGLGKPQP RDRGPRLLGE PRWGQASSDR AAVCGECGKS 120
FRQMSDLVKH QRTHTGEKPY KCGVCGKGFG DSSARIKHQR THSGEKPYRA RPPAQGPPKI 180
PRSRIPAGER PTICGECGKS FRQSSDLVKH QRTHTGEKPY KCGICGKGFG DSSARIKHQR 240
THRGEQPPRP VVPRRQPSRA ATAATQGPKA QDKPYICTDC GKRFVLSCSL LSHQRSHLGP 300
KPFGCDVCGK EFARGSDLVK HLRVHTGEKP YLCPECGKGF ADSSARVKHL RTHSGERPHA 360
CPECDRTFSL SSTLLRHRLT HMEPQDFSFP GYPLPALIPS PPPPPLGTSP PLTPRSPSHS 420
GEPFGLPGLE PEPGGPQAGE PPPPLAGDKP HKCPECGKGF RRSSDLVKHH RVHTGEKPYL 480
CPECGKGFAD SSARVKHLRT HRGERARPPP PSTLLRPHNP PGPVPMAPRP RVRAQPSGPS 540
QPHVCGFCGK EFPRSSDLVK HRRTHTGEKP YKCAECGKGF GDSSARIKHQ RGHLVLTPFG 600
IGDGRARPLK QEAATGLE 618 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
  
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS