CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041972
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 180 
Protein Synonyms/Alias
 Zinc finger protein 180 (HHZ168), isoform CRA_d 
Gene Name
 ZNF180 
Gene Synonyms/Alias
 hCG_20343 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
95LATAVGKKDSTSKQRubiquitination[1]
173KSDETGEKSGLNSSLubiquitination[1]
305PFEESQYKCSETSHSubiquitination[1]
466QRIHTGEKPYECNQCubiquitination[1]
494QRTHTGEKPFECNQCubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 667 AA 
Protein Sequence
MRACAGSTRE AGSGAQDLST LLCLEESMEE QDEKPPEPPK ACAQEGVNFK IVTVDFTREE 60
QGTWNPAQRT LDRDVILENH RDLVSWDLAT AVGKKDSTSK QRIFDEEPAN GVKIERFTRD 120
DPWLSSCEEV DDCKDQLEKQ QEKQEILLQE VAFTQRKAVI HERVCKSDET GEKSGLNSSL 180
FSSPVIPIRN HFHKHVSHAK KWHLNAAVNS HQKINENETL YENNECGKPP QSIHLIQFTR 240
TQTKDKCYGF SDRIQSFCHG TPLHIHEKIH GGGKTFDFKE CGQVLNPKIS HNEQQRIPFE 300
ESQYKCSETS HSSSLTQNMR NNSEEKPFEC NQCGKSFSWS SHLVAHQRTH TGEKPYECSE 360
CGKSFSRSSH LVSHQRTHTG EKPYRCNQCG KSFSQSYVLV VHQRTHTGEK PYECNQCGKS 420
FRQSYKLIAH QRTHTGEKPY ECNQCGKSFI QSYKLIAHQR IHTGEKPYEC NQCGKSFSQS 480
YKLVAHQRTH TGEKPFECNQ CGKSFSWSSQ LVAHQRTHTG EKPYECSECG KSFNRSSHLV 540
MHQRIHTGEK PYECNQCGKS FSQSYVLVVH QRTHTGEKPY ECSQCGKSFR QSSCLTQHQR 600
THTGEKPFEC NQCGKTFSLS ARLIVHQRTH TGEKPFTCIQ CGKAFINSYK LIRHQATHTE 660
EKLYECN 667 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS