CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029262
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 NFAT homolog, isoform B 
Protein Synonyms/Alias
  
Gene Name
 NFAT 
Gene Synonyms/Alias
 CG11172; Dmel_CG11172 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
113PSKRQPGKGLPGKLHacetylation[1]
118PGKGLPGKLHTITRTacetylation[1]
129ITRTGPGKMVPGKRIacetylation[1]
134PGKMVPGKRIPQRPHacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1457 AA 
Protein Sequence
MRFTYNQYKH YESGYRIPSK MHNLSHNNNN NSNNNNNGGG HTNNNNNGNN SGHHYAHHNN 60
SNNGGNNNTN FQAYQHHYKS NFGMRMTMST NSTMSARIHR KGFRIPSKRQ PGKGLPGKLH 120
TITRTGPGKM VPGKRIPQRP HPPPCDNSND SGLGFDQHTE LRSSAGAGGV TDPAANGGSG 180
SNSGQRSSLL VNSALTNTVA AAAAAAAAAV ASNTLQQHQQ HHQQQQQQQQ QQQQQQQQQQ 240
QQQQQQQHSP QQHLIRAIPV SRSRNNTKVM AHCLEDLDLI SASSEDSSTI ATPAGLDEDT 300
GFVNDTKTTT TGGNSSSDPF GGVFQATEAA VAAAVNAFNL QQQQHSVQQQ QHQLFQYNGL 360
LLQPQQQLQQ QQSHHQQQQQ QQQHHRHGKH IKRKKLECNQ VELDNDDACS EDEFIRKIAS 420
SVTMSPTLEA TPSPPPIVAS VAPATTIVSL LPLISSGNSN NNNNNNNIET KFISARNVTR 480
VANKRQPTTP LNSVASSNDG QVQLEILSQP EQQHRARYQT EGSRGAVKDR SGNGFPIVRL 540
TGYDKVAVLQ VFIGTDIGRV APHMFYQACK VAGKNSTQCN EKKVDGTMVI EIDFKPETDM 600
TITCDCVGIL KERNVDVEHR FPEHLAQKNK KKSTRCRMVF RTQLTRDDGT TETLQVCSNP 660
IICTQPPGVP EICKKSLNSC PVDGGLELFI IGKNFLKDTH VVFQETYDSV NGDDPATEIA 720
VRQQLIGGTA ALWEQSVLPD KEYLHQTHLI CTVPPYLHQN ILKPVQVQVS IVSSGKKSEP 780
HTFTYTAKGQ YTTLAAASTL SNTIHAQDVS GFMDTTSASN ASGSSGWSAA GGSGNNTSTG 840
DNVEAKHEID SGMMPPPITT QIPMGVRRSS LPSVTPMITD QQLVHLNAVA ASAEALKTEL 900
DDSNSHSPLT GESTPDSPNA ALQYHRFARK PSLDTIMYDQ SNSLPGFPTV VAPATAAAVA 960
AAVDIDPTAV AVAVELAVKN EIVKHVVQQH QQMQEQMHEQ QQQQQQQQQQ QQQQQQQQPQ 1020
QQQQQQVHKF IDELTKSTSV VSSNGTTEPA LFTTSAVIDH ALTDILQAKV GIAPPNVVLE 1080
RSLSLSSTNS SSSMSGSESS PNSSPLTQDI ILNSEPAAAL AGAAALGGPA PVDVTGGLST 1140
DIIMNPAVSP STILCSANGA ATAVVPNILA PHQVTMANSI LNDIAMQPEP TQQDAAVAAL 1200
ALSNIMMSPP TAASGVGVGD TLPPTPATMQ PEVAATATST AVSNMIIKAA ADFITTQEQE 1260
QHHYHHHGRI HSHSPQAAVG VSGNPAETAS DPLVDLLLNH SNTPETAAAA AAAVAVEAAN 1320
FQSMNHSHHS HHGHHGHSHG HGHSRVTGHV SGHVTSHHRG HHLPVVPPTP QESLIVALAS 1380
ENALQKSVAT AAVTTNGAVM TQQASAPNTA GSILPAAVGA VAAAAAVAVQ PPIPQELTTM 1440
SDQDLISYIN PSTFDQL 1457 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.
 GO:0046580; P:negative regulation of Ras protein signal transduction; IGI:FlyBase.
 GO:2000301; P:negative regulation of synaptic vesicle exocytosis; IDA:FlyBase.
 GO:2001020; P:regulation of response to DNA damage stimulus; IGI:FlyBase.
 GO:0009651; P:response to salt stress; IMP:FlyBase. 
Interpro
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set.
 IPR002909; IPT_TIG_rcpt.
 IPR008366; NFAT.
 IPR008967; p53-like_TF_DNA-bd.
 IPR011539; RHD. 
Pfam
 PF00554; RHD
 PF01833; TIG 
SMART
 SM00429; IPT 
PROSITE
 PS50254; REL_2 
PRINTS