| Tag | Content |
|---|
| CPLM ID | CPLM-013288 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glucoside xylosyltransferase 1 |
Protein Synonyms/Alias | Glycosyltransferase 8 domain-containing protein 3 |
Gene Name | GXYLT1 |
Gene Synonyms/Alias | GLT8D3 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 307 | DILMPLLKKYKLNIT | ubiquitination | [1] | | 308 | ILMPLLKKYKLNITW | ubiquitination | [1] | | 374 | RGVYHDDKQPAFRAV | ubiquitination | [1] | | 400 | DNIRSLLKPLELELQ | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose. |
Sequence Annotation | MOD_RES 268 268 Phosphothreonine (By similarity).
CARBOHYD 173 173 N-linked (GlcNAc...) (Potential).
CARBOHYD 237 237 N-linked (GlcNAc...).
CARBOHYD 278 278 N-linked (GlcNAc...). |
Keyword | Alternative splicing; Complete proteome; Glycoprotein; Glycosyltransferase; Membrane; Phosphoprotein; Reference proteome; Signal-anchor; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 440 AA |
Protein Sequence | MRRYLRVVVL CVACGFCSLL YAFSQLAVSL EEGTGGGGGK PQAAVASWLA GGGRGAVRGA 60
GVAGPAAHPG VSDRCKDFSL CYWNPYWMLP SDVCGMNCFW EAAFRYSLKI QPVEKMHLAV 120
VACGERLEET MTMLKSAIIF SIKPLQFHIF AEDQLHHSFK GRLDNWSFLQ TFNYTLYPIT 180
FPSENAAEWK KLFKPCASQR LFLPLILKEV DSLLYVDTDI LFLRPVDDIW SLLKKFNSTQ 240
IAAMAPEHEE PRIGWYNRFA RHPYYGKTGV NSGVMLMNMT RMRRKYFKND MTTVRLQWGD 300
ILMPLLKKYK LNITWGDQDL LNIVFFHNPE SLFVFPCQWN YRPDHCIYGS NCQEAEEGGI 360
FILHGNRGVY HDDKQPAFRA VYEALRNCSF EDDNIRSLLK PLELELQKTV HTYCGKIYKI 420
FIKQLAKSVR DRYARSPKEK 440 |
Gene Ontology | GO:0000139; C:Golgi membrane; TAS:Reactome. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0035252; F:UDP-xylosyltransferase activity; IDA:UniProtKB. GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome. GO:0016266; P:O-glycan processing; IDA:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |