CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034485
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Forkhead box protein P1 
Protein Synonyms/Alias
  
Gene Name
 Foxp1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
471IRRRYSDKYNVPISSacetylation[1]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 706 AA 
Protein Sequence
MMQESGSETK SNGSAIQNGS SGGNHLLECG ALRDTRSNGE APAVDLGAAD LAHVQQQQQQ 60
ALQVARQLLL QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQVSG LKSPKRNDKQ 120
PALQVPVSVA MMTPQVITPQ QMQQILQQQV LSPQQLQVLL QQQQALMLQQ QLQEFYKKQQ 180
EQLQLQLLQQ QHAGKQPKEQ QQVATQQLAF QQQLLQMQQL QQQHLLSLQR QGLLTIQPGQ 240
PALPLQPLAQ GMIPTELQQL WKEVTSAHTA EETTSSNHSS LDLTSTCVSS SAPSKSSLIM 300
NPHASTNGQL SVHTPKRESL SHEEHPHSHP LYGHGVCKWP GCEAVCDDFP AFLKHLNSEH 360
ALDDRSTAQC RVQMQVVQQL ELQLAKDKER LQAMMTHLHV KSTEPKAAPQ PLNLVSSVTL 420
SKSASEASPQ SLPHTPTTPT APLTPVTQGP SVITTTSMHT VGPIRRRYSD KYNVPISSAD 480
IAQNQEFYKN AEVRPPFTYA SLIRQAILES PEKQLTLNEI YNWFTRMFAY FRRNAATWKN 540
AVRHNLSLHK CFVRVENVKG AVWTVDEVEF QKRRPQKISG NPSLIKNMQS SHAYCTPLNA 600
ALQASMAENS IPLYTTASMG NPTLGSLASA IREELNGAME HTNSNESDSS PGRSPMQAVH 660
PIHVKEEPLD PEEAEGPLSL VTTANHSPDF DHDRDYEDEP VNEDME 706 
Gene Ontology
 GO:0005737; C:cytoplasm; IBA:RefGenome.
 GO:0005667; C:transcription factor complex; IBA:RefGenome.
 GO:0003682; F:chromatin binding; IDA:MGI.
 GO:0008301; F:DNA binding, bending; IBA:RefGenome.
 GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
 GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0008134; F:transcription factor binding; IBA:RefGenome.
 GO:0055007; P:cardiac muscle cell differentiation; IMP:MGI.
 GO:0033152; P:immunoglobulin V(D)J recombination; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0030324; P:lung development; IGI:MGI.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0007389; P:pattern specification process; IBA:RefGenome.
 GO:2000727; P:positive regulation of cardiac muscle cell differentiation; IMP:MGI.
 GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.
 GO:0002639; P:positive regulation of immunoglobulin production; IMP:MGI.
 GO:0002053; P:positive regulation of mesenchymal cell proliferation; IGI:MGI.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.
 GO:0002329; P:pre-B cell differentiation; IMP:MGI.
 GO:0060043; P:regulation of cardiac muscle cell proliferation; IMP:MGI.
 GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
 GO:0045214; P:sarcomere organization; IGI:MGI.
 GO:0007519; P:skeletal muscle tissue development; IGI:MGI.
 GO:0048745; P:smooth muscle tissue development; IGI:MGI. 
Interpro
 IPR001766; TF_fork_head.
 IPR018122; TF_fork_head_CS.
 IPR011991; WHTH_DNA-bd_dom.
 IPR015880; Znf_C2H2-like. 
Pfam
 PF00250; Fork_head 
SMART
 SM00339; FH
 SM00355; ZnF_C2H2 
PROSITE
 PS00658; FORK_HEAD_2
 PS50039; FORK_HEAD_3 
PRINTS
 PR00053; FORKHEAD.