CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037348
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cytoskeleton-associated protein 2 
Protein Synonyms/Alias
  
Gene Name
 CKAP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
180NTSSVTVKSNRSSNMubiquitination[1]
245EKELLQSKTALSSVKubiquitination[1]
460IVDILTMKSQEKANLubiquitination[1]
464LTMKSQEKANLGENMubiquitination[1, 2]
555TPYLQSVKKKVQFDGubiquitination[1]
568DGTNSAFKELKFLTPubiquitination[1, 3]
571NSAFKELKFLTPVRRubiquitination[3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 634 AA 
Protein Sequence
MLSSRDQRVV TSEDQVQEGT KVLKLKTKMA DKENMKRPAE SKNNTVVGKH CIPLKPSNEL 60
TNSTVVIDTH KPKDSNQTPH LLLTEDDPQS QHMTLSQAFH LKNNSKKKQM TTEKQKQDAN 120
MPKKPVLGSY RGQIVQSKIN SFRKPLQVKD ESSAATKKLS ATIPKATKPQ PVNTSSVTVK 180
SNRSSNMTAT TKFVSTTSQN TQLVRPPIRS HHSNTRDTVK QGISRTSANV TIRKGPHEKE 240
LLQSKTALSS VKTSSSQGII RNKTLSRSIA SEVIARPASL SNDKLMEKSE PVDQRRHTAG 300
KAIVDSRSAQ PKETSEERKA RLSEWKAGKG RVLKRPPNSV VTQHEPAGQN EKPVGSFWTT 360
MAEEDEQRLF TEKVNNTFSE CLNLINEGCP KEDILVTLND LIKNIPDAKK LVKYWICLAL 420
IEPITSPIEN IIAIYEKAIL AGAQPIEEMR HTIVDILTMK SQEKANLGEN MEKSCASKEE 480
VKEVSIEDTG VDVDPEKLEM ESKLHRNLLF QDCEKEQDNK TKDPTHDVKT PNTETRTSCL 540
IKYNVSTTPY LQSVKKKVQF DGTNSAFKEL KFLTPVRRSR RLQEKTSKLP DMLKDHYPCV 600
SSLEQLTELG RETDAFVCRP NAALCRVYYE ADTT 634 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0015630; C:microtubule cytoskeleton; IDA:HPA. 
Interpro
 IPR026166; CKAP2.
 IPR026165; CKAP2_fam. 
Pfam
  
SMART
  
PROSITE
  
PRINTS