CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040285
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Epidermal growth factor receptor substrate 15 
Protein Synonyms/Alias
  
Gene Name
 Eps15 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
227VSPAEKAKYDEIFLKubiquitination[1]
386RESINLQKLQAQKQQubiquitination[1]
505FKDDPFGKIDPFGGDubiquitination[1]
662PGKRPINKLDSSDPLubiquitination[1]
670LDSSDPLKLNDPFQPubiquitination[1]
685FPGNDSPKEKDPDMFubiquitination[1]
687GNDSPKEKDPDMFCDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 764 AA 
Protein Sequence
MAAAAQLSLT QLSSGNPVYE KYYRQVEAGN TGRVLALDAA AFLKKSGLPD LILGKIWDLA 60
DTDGKGVLSK QEFFVALRLV ACAQNGLEVS LSSLSLAVPP PRFHDSSSPL LTSGPSVAEL 120
PWAVKSEDKA KYDAIFDSLS PVDGFLSGDK VKPVLLNSKL PVEILGRVWE LSDIDHDGKL 180
DRDEFAVAMF LVYCALEKEP VPMSLPPALV PPSKRKTWVV SPAEKAKYDE IFLKTDKDMD 240
GYVSGLEVRE TFLKTGLPSA LLAHIWSLCD TKGCGKLSKD QFALAFHLIN QKLIKGIDPP 300
HSLTPEMIPP SDRSSLQKNI TGSSPVADFS AIKELDTLNN EIVDLQREKN NVEQDLKEKE 360
DTVKQRTSEV QDLQDEVQRE SINLQKLQAQ KQQVQELLGE LDEQKAQLEE QLQEVRKKCA 420
EEAQLVRSSP EIAPSDVTDE SEAVTVAGNE KVTPRFDDDK HSKEEDPFNV ESSSLTDAVA 480
DTNLDFFQSD PFVGSDPFKD DPFGKIDPFG GDPFKGSDPF ASDCFFKQTS TDPFTTSSTD 540
PFSASSNSSN TSVETWKHND PFAPGGTVVA AASDSATDPF ASVFGNESFG DGFADFSTLS 600
KVNNEDAFNP TISSSTSSVT IAKPMLEETA SKSEDVPPAL PPKVGTPTRP CPPPPGKRPI 660
NKLDSSDPLK LNDPFQPFPG NDSPKEKDPD MFCDPFTSST TTNKEADPSN FANFSAYPSE 720
EDMIEWAKRE SEREEEQRLA RLNQQEQEDL ELAIALSKSE ISEA 764 
Gene Ontology
 GO:0060170; C:cilium membrane; IDA:MGI.
 GO:0005905; C:coated pit; IDA:MGI.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR000261; EPS15_homology.
 IPR003903; Ubiquitin-int_motif. 
Pfam
  
SMART
 SM00054; EFh
 SM00027; EH
 SM00726; UIM 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS50031; EH
 PS50330; UIM 
PRINTS