CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003602
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Superoxide dismutase [Cu-Zn] 
Protein Synonyms/Alias
 Bacteriocuprein 
Gene Name
 sodC 
Gene Synonyms/Alias
 b1646; JW1638 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
57LEFSPDLKALPPGEHacetylation[1]
100LDPQNTGKHEGPEGAacetylation[1]
123LVVNNDGKATDAVIAacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Destroys radicals which are normally produced within the cells and which are toxic to biological systems. 
Sequence Annotation
 METAL 67 67 Copper; catalytic.
 METAL 69 69 Copper; catalytic.
 METAL 92 92 Copper; catalytic.
 METAL 92 92 Zinc; structural.
 METAL 101 101 Zinc; structural.
 METAL 109 109 Zinc; structural.
 METAL 112 112 Zinc; structural.
 METAL 147 147 Copper; catalytic.
 DISULFID 74 169  
Keyword
 3D-structure; Antioxidant; Complete proteome; Copper; Direct protein sequencing; Disulfide bond; Metal-binding; Oxidoreductase; Periplasm; Reference proteome; Signal; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 173 AA 
Protein Sequence
MKRFSLAILA LVVATGAQAA SEKVEMNLVT SQGVGQSIGS VTITETDKGL EFSPDLKALP 60
PGEHGFHIHA KGSCQPATKD GKASAAESAG GHLDPQNTGK HEGPEGAGHL GDLPALVVNN 120
DGKATDAVIA PRLKSLDEIK DKALMVHVGG DNMSDQPKPL GGGGERYACG VIK 173 
Gene Ontology
 GO:0030288; C:outer membrane-bounded periplasmic space; IDA:EcoCyc.
 GO:0005507; F:copper ion binding; IDA:EcoliWiki.
 GO:0004784; F:superoxide dismutase activity; IDA:EcoCyc.
 GO:0008270; F:zinc ion binding; IDA:EcoliWiki.
 GO:0019430; P:removal of superoxide radicals; IBA:RefGenome. 
Interpro
 IPR024134; SOD_Cu/Zn_/chaperones.
 IPR018152; SOD_Cu/Zn_BS.
 IPR001424; SOD_Cu_Zn_dom. 
Pfam
 PF00080; Sod_Cu 
SMART
  
PROSITE
 PS00087; SOD_CU_ZN_1
 PS00332; SOD_CU_ZN_2 
PRINTS