UniProt Accession

 H0Y9Y0_HUMAN; H0Y9Y0 

Genbank Protein ID

 AC114744; AC116651 

Genbank Nucleotide ID

  

Protein Name

 F-box/LRR-repeat protein 5 

Protein Synonyms/Alias

  

Gene Name

 FBXL5 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
161	MKWSQLTKTGSLWKH	ubiquitination	[1]
197	EPDDEWVKNRKDESR	ubiquitination	[2, 3]
324	ITDVALEKISRALGI	ubiquitination	[1, 2, 3]
341	SHQSGFLKTSTSKIT	ubiquitination	[1]
346	FLKTSTSKITSTAWK	ubiquitination	[1]
355	TSTAWKNKDITMQST	ubiquitination	[1]
512	LIYFGSEKSDQETGR	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 612 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR001810; F-box_dom_cyclin-like.
 IPR006553; Leu-rich_rpt_Cys-con_subtyp. 

Pfam

  

SMART

 SM00256; FBOX
 SM00367; LRR_CC 

PROSITE

 PS50181; FBOX 

PRINTS