CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032271
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 C11orf30 protein 
Protein Synonyms/Alias
 Protein EMSY 
Gene Name
 C11orf30 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
402STRLPSPKSLVSAPTubiquitination[1]
424KQHQQSPKQQLYQVQubiquitination[1]
568SLATLGGKIISSNIVubiquitination[1]
590TTIPMTSKPNVIVVQubiquitination[1]
598PNVIVVQKTTGKGTTubiquitination[1]
602VVQKTTGKGTTIQGLubiquitination[1]
612TIQGLPGKNVVTTLLubiquitination[1, 2, 3]
625LLNAGGEKTIQTVPTubiquitination[1]
635QTVPTGAKPAILTATubiquitination[1]
654KMIVTQPKGIGSTVQubiquitination[1, 3]
665STVQPAAKIIPTKIVubiquitination[1]
670AAKIIPTKIVYGQQGubiquitination[1, 3]
684GKTQVLIKPKPVTFQubiquitination[1]
725NSSIQEGKEEPQNYTubiquitination[1, 2]
805QQTTVKEKLESKPRQubiquitination[1, 4]
830PIQMTQEKRHSPESPubiquitination[1, 2]
965LTQSQSAKQQKLSQPubiquitination[1, 2, 5]
968SQSAKQQKLSQPPLEubiquitination[1, 2]
982EQTQLQVKTLQCFQTubiquitination[1]
1018QLSIRHQKLTPLQQEubiquitination[1]
1043TQHPMVAKDRQLPTLubiquitination[1]
1158SPIQASEKTAVSDILubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [5] Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
 Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR.
 J Biol Chem. 2011 Dec 2;286(48):41530-8. [PMID: 21987572
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1337 AA 
Protein Sequence
MPVVWPTLLD LSRDECKRIL RKLELEAYAG VISALRAQGD LTKEKKDLLG ELSKVLSIST 60
ERHRAEVRRA VNDERLTTIA HKMNLSLYLG ERPSYSMSGP NSSSEWSIEG RRLVPLMPRL 120
VPQTAFTVTA NAVANAAIQH NASLPVPAET GSKEVVVCYS YTSTTSTPTS TPVPSGSIAT 180
VKSPRPASPA SNVVVLPSGS TVYVKSVSCS DEDEKPRKRR RTNSSSSSPV VLKEVPKAVV 240
PVSKTITVPV SGSPKMSNIM QSIANSLPPH MSPVKITFTK PSTQTTNTTT QKVIIVTTSP 300
SSTFVPNILS KSHNYAAVTK LVPTSVIAST TQKPPVVITA SQSSLVSNSS SGSSSSTPSP 360
IPNTVAVTAV VSSTPSVVMS TVAQGVSTSA IKMASTRLPS PKSLVSAPTQ ILAQFPKQHQ 420
QSPKQQLYQV QQQTQQQVAQ PSPVSHQQQP QQSPLPPGIK PTIQIKQESG VKIITQQVQP 480
SKILPKPVTA TLPTSSNSPI MVVSSNGAIM TTKLVTTPTG TQATYTRPTV SPSIGRMAAT 540
PGAATYVKTT SGSIITVVPK SLATLGGKII SSNIVSGTTT KITTIPMTSK PNVIVVQKTT 600
GKGTTIQGLP GKNVVTTLLN AGGEKTIQTV PTGAKPAILT ATRPITKMIV TQPKGIGSTV 660
QPAAKIIPTK IVYGQQGKTQ VLIKPKPVTF QATVVSEQTR QLVTETLQQA SRVAEAGNSS 720
IQEGKEEPQN YTDSSSSSTE SSQSSQDSQP VVHVIASRRQ DWSEHEIAME TSPTIIYQDV 780
SSESQSATST IKALLELQQT TVKEKLESKP RQPTIDLSQM AVPIQMTQEK RHSPESPSIA 840
VVESELVAEY ITTERTDEGT EVAFPLLVSH RSQPQQPSQP QRTLLQHVAQ SQTATQTSVV 900
VKSIPASSPG AITHIMQQAL SSHTAFTKHS EELGTEEGEV EEMDTLDPQT GLFYRSALTQ 960
SQSAKQQKLS QPPLEQTQLQ VKTLQCFQTK QKQTIHLQAD QLQHKLPQMP QLSIRHQKLT 1020
PLQQEQAQPK PDVQHTQHPM VAKDRQLPTL MAQPPQTVVQ VLAVKTTQQL PKLQQAPNQP 1080
KIYVQPQTPQ SQMSLPASSE KQTASQVEQP IITQGSSVTK ITFEGRQPPT VTKITGGSSV 1140
PKLTSPVTSI SPIQASEKTA VSDILKMSLM EAQIDTNVEH MIVDPPKKAL ATSMLTGEAG 1200
SLPSTHMVVA GMANSTPQQQ KCRESCSSPS TVGSSLTTRK IDPPAVPATG QFMRIQNVGQ 1260
KKAEESPAEI IIQAIPQYAI PCHSSSNVVV EPSGLLELNN FTSQQLDDEE TAMEQDIDSS 1320
TEDGTEPSPS QSSAERS 1337 
Gene Ontology
  
Interpro
 IPR005491; ENT_N. 
Pfam
 PF03735; ENT 
SMART
  
PROSITE
 PS51138; ENT 
PRINTS