| Tag | Content |
|---|
| CPLM ID | CPLM-024364 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Peptidyl-prolyl cis-trans isomerase G |
Protein Synonyms/Alias | PPIase G; Peptidyl-prolyl isomerase G; Cyclophilin G; Rotamase G |
Gene Name | Ppig |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 180 | SCGELIPKSKVKKEE | acetylation | [1] |
|
Reference | [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways. Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y. Mol Cell. 2013 Jun 27;50(6):919-30. [ PMID: 23806337] |
Functional Description | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing (By similarity). |
Sequence Annotation | DOMAIN 11 176 PPIase cyclophilin-type.
MOD_RES 252 252 Phosphoserine (By similarity).
MOD_RES 254 254 Phosphoserine (By similarity).
MOD_RES 255 255 Phosphoserine (By similarity).
MOD_RES 257 257 Phosphoserine (By similarity).
MOD_RES 313 313 Phosphoserine (By similarity).
MOD_RES 343 343 Phosphoserine.
MOD_RES 345 345 Phosphoserine.
MOD_RES 354 354 Phosphoserine (By similarity).
MOD_RES 356 356 Phosphothreonine (By similarity).
MOD_RES 395 395 Phosphoserine (By similarity).
MOD_RES 411 411 Phosphoserine (By similarity).
MOD_RES 413 413 Phosphoserine (By similarity).
MOD_RES 685 685 Phosphoserine (By similarity).
MOD_RES 688 688 Phosphoserine (By similarity).
MOD_RES 694 694 Phosphoserine (By similarity).
MOD_RES 742 742 Phosphoserine.
MOD_RES 743 743 Phosphoserine.
MOD_RES 746 746 Phosphothreonine.
MOD_RES 751 751 Phosphoserine (By similarity). |
Keyword | Complete proteome; Isomerase; Nucleus; Phosphoprotein; Reference proteome; Rotamase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 752 AA |
Protein Sequence | MGIKVQRPRC FFDIAINNQP AGRVVFELFS DVCPKTCENF RCLCTGEKGT GKSTQKPLHY 60
KSCLFHRVVK DFMVQGGDFS EGNGRGGESI YGGFFEDESF AVKHNKEFLL SMANRGKDTN 120
GSQFFITTKP TPHLDGHHVV FGQVISGQEV VREIENQKTD AASKPFAEVR ILSCGELIPK 180
SKVKKEEKKR HKSSSSSSSS DSDSSSDSQS SSESSDSESA SEEKSRKRKK KHRKNSRKHK 240
KEKKKRKKSK KSPSSESEAE NVDAQPQSTV RPEEIPPIPE NRFLMRKSPP KADDKERKNR 300
ERERERECNP PNSQPASYQR RFLVTRSGRK IKGRGPRRYR TPSRSRSRDR FRRSETPPHW 360
RQEMQRAQRM RVSSGERWIK GDKSELNEIK ENQRSPVRVK EKKITDHRHM SESPNRKVEK 420
EKKAKDHKSE SKERDIRRNS EKDDKYNKNK VKKRGKSKSR SKSKERSKSK ERDSKHSRHE 480
DKRVRSRSKE RDHETTKEKE KPLDPKGKDQ ERSRSKENSK QVESKSNEHD HSKSKEKDRR 540
AQSRSRERDL TKSKHSYNSR TRERSRSRDR SRRVRSRSHD RDRSRSKEYH RYREQEYRRR 600
GRSRSRDRRT PGRSRSKDRR RRRRDSRSSE REESQSRNKD KYRSQESKSS HRKENSEGEK 660
RTYSKSRDHN SSSNNREKKA DREQSPVSKT KQSSQDNEVK SSTLKNQEDE KTRSPVEKEN 720
QKSKGQENDH VHDKNKKCDH ESSPGTDEDK SG 752 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:Compara. GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW. GO:0006457; P:protein folding; IEA:UniProtKB-KW. GO:0000413; P:protein peptidyl-prolyl isomerization; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |