UniProt Accession

 MNTR_ECOLI; P0A9F1; P75787 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC73904.1; BAA35488.1 

Protein Name

 Transcriptional regulator MntR 

Protein Synonyms/Alias

 Manganese transport regulator 

Gene Name

 mntR 

Gene Synonyms/Alias

 ybiQ; b0817; JW0801 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
100	FLTAEGEKLAQESRE	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP. 

Sequence Annotation

 DOMAIN 34 95 HTH dtxR-type.  

Keyword

 3D-structure; Activator; Complete proteome; Cytoplasm; DNA-binding; Manganese; Reference proteome; Repressor; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 155 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:EcoCyc.
 GO:0046914; F:transition metal ion binding; IEA:InterPro.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:EcoCyc.
 GO:2000144; P:positive regulation of DNA-dependent transcription, initiation; IEP:EcoCyc.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR001367; Fe_dep_repressor.
 IPR022689; Fe_dep_repressor_HTH_DtxR.
 IPR022687; Fe_dep_repressor_HTH_DtxR_N.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF02742; Fe_dep_repr_C
 PF01325; Fe_dep_repress 

SMART

 SM00529; HTH_DTXR 

PROSITE

 PS50944; HTH_DTXR 

PRINTS