UniProt Accession

 KV109_HUMAN; P01601 

Genbank Protein ID

 K01322; K01324; V00558 

Genbank Nucleotide ID

 AAA58930.1; AAA58932.1; CAA23824.1 

Protein Name

 Ig kappa chain V-I region HK101 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
61	WLAWYQQKPEKAPKS	acetylation	[1]
64	WYQQKPEKAPKSLIY	acetylation	[1]

Reference

 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

  

Sequence Annotation

 REGION 23 45 Framework-1.
 REGION 46 56 Complementarity-determining-1.
 REGION 57 71 Framework-2.
 REGION 72 78 Complementarity-determining-2.
 REGION 79 110 Framework-3.
 REGION 111 >117 Complementarity-determining-3.
 DISULFID 45 110 By similarity.  

Keyword

 Complete proteome; Disulfide bond; Immunoglobulin domain; Immunoglobulin V region; Reference proteome; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 117 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; NAS:UniProtKB.
 GO:0005886; C:plasma membrane; TAS:Reactome.
 GO:0003823; F:antigen binding; NAS:UniProtKB.
 GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
 GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
 GO:0045087; P:innate immune response; TAS:Reactome. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013106; Ig_V-set.
 IPR003596; Ig_V-set_subgr. 

Pfam

 PF07686; V-set 

SMART

 SM00406; IGv 

PROSITE

 PS50835; IG_LIKE 

PRINTS