CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028114
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sec23, isoform A 
Protein Synonyms/Alias
 Sec23, isoform B 
Gene Name
 Sec23 
Gene Synonyms/Alias
 sec23; CG1250; Dmel_CG1250 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
337RFMKKAIKHYDALALacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 773 AA 
Protein Sequence
MTTYEEFIQQ NEDRDGVRLT WNVWPSSRIE ASRLVVPLAC LYQPLKERPD LPPIQYEPVL 60
CTRSNCRAIL NPLCQVDYRA KLWVCNFCFQ RNPFPPQYAA ISEQHQPAEL IPGFSTIEYT 120
ITRAPTMPPV FIFLVDTCMD EEELDALKDS LQMSLSLLPT NALVGLITFG KMIQVHELGA 180
EGCSKSYVFR GTKDLTAKQV QDMLGIGRGA APGPQQQQHL PGQPAGAAAP VPPAHRFLQP 240
IGQCDAALGD LLSELQRDPW PVPQGKRYLR STGAALSIAV GLLECTYPNT GGRIMTFVGG 300
PCSQGPGQVV DDELKHPIRS HHDIHKDNVR FMKKAIKHYD ALALRAATNG HSVDIYSCAL 360
DQTGLLEMKQ LCNSTGGHMV MGDSFNSSLF KQTFQRVFAR DGRNDLKMAF NATLEVKCSR 420
ELKISGGIGS CVSLNVKSPS VSDVEIGMGN TVQWKLCTLN PSSTVAYFFE VVNQHAAPIP 480
QGGRGCIQFI TQYQHPSGQR RIRVTTLARN WADATSNVHH ISAGFDQEAA AVLMARMVVY 540
RAETDEGPDI LRWVDRQLIR LCQKFGEYSK DDPNSFRLSQ NFSLFPQFMY HLRRSQFLQV 600
FNNSPDETTF YRHMLMREDL TQSLIMIQPI LYSYSFNGPP EPVLLDTASI QADRILLMDT 660
FFQILIYHGE TIAQWRALKY QDMPEYENFK QLLQAPVDDA QEILQTRFPM PRYIDTEHGG 720
SQARFLLSKV NPSQTHNNMY AYGQDGGAPV LTDDVSLQLF MEHLKKLAVS TTT 773 
Gene Ontology
 GO:0030127; C:COPII vesicle coat; IEA:InterPro.
 GO:0005783; C:endoplasmic reticulum; IDA:FlyBase.
 GO:0030134; C:ER to Golgi transport vesicle; TAS:FlyBase.
 GO:0005795; C:Golgi stack; IDA:FlyBase.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0071711; P:basement membrane organization; IMP:FlyBase.
 GO:0035293; P:chitin-based larval cuticle pattern formation; IMP:FlyBase.
 GO:0007029; P:endoplasmic reticulum organization; IMP:FlyBase.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro.
 GO:0007030; P:Golgi organization; IMP:FlyBase.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0035149; P:lumen formation, open tracheal system; IMP:FlyBase.
 GO:0030011; P:maintenance of cell polarity; IMP:FlyBase.
 GO:0016203; P:muscle attachment; IMP:FlyBase.
 GO:0050774; P:negative regulation of dendrite morphogenesis; IMP:FlyBase.
 GO:0048812; P:neuron projection morphogenesis; IMP:FlyBase.
 GO:0022409; P:positive regulation of cell-cell adhesion; IMP:FlyBase.
 GO:0048081; P:positive regulation of cuticle pigmentation; IMP:FlyBase.
 GO:0003331; P:positive regulation of extracellular matrix constituent secretion; IMP:FlyBase.
 GO:0034394; P:protein localization to cell surface; IMP:FlyBase.
 GO:0008360; P:regulation of cell shape; IMP:FlyBase. 
Interpro
 IPR007123; Gelsolin_dom.
 IPR006900; Sec23/24_helical_dom.
 IPR006896; Sec23/24_trunk_dom.
 IPR012990; Sec23_24_beta_S.
 IPR002035; VWF_A.
 IPR006895; Znf_Sec23_Sec24. 
Pfam
 PF00626; Gelsolin
 PF08033; Sec23_BS
 PF04815; Sec23_helical
 PF04811; Sec23_trunk
 PF04810; zf-Sec23_Sec24 
SMART
  
PROSITE
  
PRINTS