CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026902
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ16146 fis, clone BRAMY2040159, highly similar to Homo sapiens MRIP-1 mRNA 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
18KGDPLIYKDFRGDSGubiquitination[1]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Metal-binding; Repeat; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 743 AA 
Protein Sequence
MISQFFILSS KGDPLIYKDF RGDSGGRDVA ELFYRKLTGL PGDESPVVMD YGYVQTTSTE 60
MLRNFIQTEA VVSKPFSLFD LSSVGLFGAE TQQSKVAPSS AASRPVLSSR SDQSQKNEVF 120
LDVVERLSVL IASNGSLLKV DVQGEIRLKS FLPSGSEMRI GLTEEFCVGK SELRGYGPGI 180
RVDEVSFHSS VNLDEFESHR ILRLQPPQGE LTVMRYQLSD DLPSPLPFRL FPSVQWDRGS 240
GRLQVYLKLR CDLLSKSQAL NVRLHLPLPR GVVSLSQELS SPEQKAELAE GALRWDLPRV 300
QGGSQLSGLF QSRKGADLDR EKKAAECKVD SIGSGRAIPI KQGILLKRSG KSLNKEWKKK 360
YVTLCDNGLL TYHPSLHDYM QNIHGKEIDL LRTTVKVPGK RLPRATPATA PGTSPRANGL 420
SVERSNTQLG GGTEAEESFE FVVVSLTGQT WHFEASTAEE RELWVQSVQA QILASLQGCR 480
SAKDKTRLGN QNAALAVQAV RTVRGNSFCI DCDAPNPDWA SLNLGALMCI ECSGIHRHLG 540
AHLSRVRSLD LDDWPPELLA VMTAMGNALA NSVWEGALGG YSKPGPDACR EEKERWIRAK 600
YEQKLFLAPL PSSDVPLGQQ LLRAVVEDDL RLLVMLLAHG SKEEVNETYG DGDGRTALHL 660
SSAMANVVFT QLLIWYGVDV RSRDARGLTP LAYARRAGSQ ECADILIQHG CPGEGCGLAP 720
TPNREPANGT NPSAELHRSP SLL 743 
Gene Ontology
 GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
 GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IEA:InterPro. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR001164; ArfGAP.
 IPR008968; Clathrin_mu_C.
 IPR018240; Clathrin_mu_CS.
 IPR011012; Longin-like_dom.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 
Pfam
 PF00928; Adap_comp_sub
 PF12796; Ank_2
 PF01412; ArfGap
 PF00169; PH 
SMART
 SM00248; ANK
 SM00105; ArfGap
 SM00233; PH 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS50115; ARFGAP
 PS00991; CLAT_ADAPTOR_M_2
 PS51072; MHD
 PS50003; PH_DOMAIN 
PRINTS
 PR00405; REVINTRACTNG.