CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036989
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 ATP-binding cassette sub-family G member 1 
Protein Synonyms/Alias
  
Gene Name
 ABCG1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
297AHLKLQEKDEGRREMubiquitination[1]
408GQCVYRGKVCNLVPYubiquitination[2]
484HRPSEEVKQTKRLKGubiquitination[2]
487SEEVKQTKRLKGLRKubiquitination[2]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 786 AA 
Protein Sequence
MVRRGWSVCT AILLARLWCL VPTHTFLSEY PEAAEYPHPG WVYWLQMAVA PGHLRAWVMR 60
NNVTTNIPSA FSGTLTHEEK AVLTVFTGTA TAVHVQVAAL ASAKLESSVF VTDCVSCKIE 120
NVCDSALQGK RVPMSGLQGS SIVIMPPSNR PLKASAASCT WSVQVQGGPH HLGVVAISGK 180
VLSAAHGAGR AYGWGFPGDP MEEGYKTLLK GISGKFNSGE LVAIMGPSGA GKSTLMNILA 240
GYRETGMKGA VLINGLPRDL RCFRKVSCYI MQDDMLLPHL TVQEAMMVSA HLKLQEKDEG 300
RREMVKEILT ALGLLSCANT RTGSLSGGQR KRLAIALELV NNPPVMFFDE PTSGLDSASC 360
FQVVSLMKGL AQGGRSIICT IHQPSAKLFE LFDQLYVLSQ GQCVYRGKVC NLVPYLRDLG 420
LNCPTYHNPA DFVMEVASGE YGDQNSRLVR AVREGMCDSD HKRDLGGDAE VNPFLWHRPS 480
EEVKQTKRLK GLRKDSSSME GCHSFSASCL TQFCILFKRT FLSIMRDSVL THLRITSHIG 540
IGLLIGLLYL GIGNEAKKVL SNSGFLFFSM LFLMFAALMP TVLTFPLEMG VFLREHLNYW 600
YSLKAYYLAK TMADVPFQIM FPVAYCSIVY WMTSQPSDAV RFVLFAALGT MTSLVAQSLG 660
LLIGAASTSL QVATFVGPVT AIPVLLFSGF FVSFDTIPTY LQWMSYISYV RYGFEGVILS 720
IYGLDREDLH CDIDETCHFQ KSEAILRELD VENAKLYLDF IVLGIFFISL RLIAYFVLRY 780
KIRAER 786 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0006810; P:transport; IEA:InterPro. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR013525; ABC_2_trans.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR020064; ABC_transptr_G1-like.
 IPR027417; P-loop_NTPase.
 IPR005284; Pigment_permease. 
Pfam
 PF01061; ABC2_membrane
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS