CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030383
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Anapc2 protein 
Protein Synonyms/Alias
 Anaphase promoting complex subunit 2; Protein Anapc2 
Gene Name
 Anapc2 
Gene Synonyms/Alias
 rCG_45762 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
697WTLEELSKVVKMPVAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 836 AA 
Protein Sequence
MEAEGVAVSV AAAAAATTTI VATDDCDSRP GQELVVAWNT VSTGLVPPAA LGLASSRTSG 60
AVPPKEEELR AAVEVLRAHG LHSVLEEWFV EVLQNDLQGN IATEFWNAIS LRENSVDEPQ 120
CLVLLLDAFG LLESRLDPYL HSLELLEKWT RLGLLMGAGA QGLREKVHTM LRGVLFFSTP 180
RTFQEMVQRL YGRFLRVYMQ SKRKGEGGTD PELEGELDSR YARRRYYRLL QSPLCAGCGS 240
DKQQCWCRQA LEQFNQLSQV LHRLSLLERV SAEAVTTTLH QVTRERMEDR CRGEYERSFL 300
REFHKWIERV VGWLGKVFLQ DNPSRPTSPE AGNTLRRWRC HVQRFFYRIY ASLRIEELFS 360
IIRDFPDSRP AIEDLKYCLE RTDQRQQLLV SLKVALETRL LHPGVNTCDI ITLYISAIKA 420
LRVLDPSMVI LEVACEPIRR YLRTREDTVR QIVAGLTGDS DGTGDLAVEL SKTDPACLET 480
GQDSEDDSGE PEDWVPDPVD ADPAKSSSKR RSSDIISLLV SIYGSKDLFI NEYRSLLADR 540
LLHQFSFSPE REIRNVELLK LRFGEAPMHF CEVMLKDMAD SRRINANIRE EDEKRPVEEQ 600
PPFGVYAVIL SSEFWPPFKD EKLEVPEDIR AALDVYCKKY EKLKAMRTLS WKHTLGLVTM 660
DVELADRTLS VAVTPVQAVV LLYFQDQASW TLEELSKVVK MPVALLRRRM SVWLQQGVLR 720
EEPPGTFSVI EEERPQDRDN MVLIDSDDES DSGMASQADQ KEEELLLFWT YIQAMLTNLE 780
SLSLERIYSM LRMFVMTGPA LAEIDLQELQ GYLQKKVRDQ QLIYSAGVYR LPKNCN 836 
Gene Ontology
 GO:0005680; C:anaphase-promoting complex; IEA:Compara.
 GO:0005634; C:nucleus; IDA:RGD.
 GO:0045773; P:positive regulation of axon extension; IMP:RGD.
 GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.
 GO:0090129; P:positive regulation of synapse maturation; IEA:Compara.
 GO:0031915; P:positive regulation of synaptic plasticity; IEA:Compara.
 GO:0070979; P:protein K11-linked ubiquitination; IEA:Compara.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR014786; APC_su2_C.
 IPR016158; Cullin_homology.
 IPR001373; Cullin_N.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF08672; APC2
 PF00888; Cullin 
SMART
 SM01013; APC2
 SM00182; CULLIN 
PROSITE
 PS50069; CULLIN_2 
PRINTS