CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001082
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Telethonin 
Protein Synonyms/Alias
 Titin cap protein 
Gene Name
 Tcap 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
98LPIFTPTKVGASKEEubiquitination[1]
103PTKVGASKEEREETPubiquitination[1]
148PPVVPVSKPGPLRRTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 167 AA 
Protein Sequence
MATSELSCQV SEENQERREA FWAEWKDLTL STRPEEGCSL HEEDTQRHET YHRQGQCQAV 60
VQRSPWLVMR LGILGRGLQE YQLPYQRVLP LPIFTPTKVG ASKEEREETP IQLRELLALE 120
TALGGQCVER QDVAEITKQL PPVVPVSKPG PLRRTLSRSM SQEAQRG 167 
Gene Ontology
 GO:0030018; C:Z disc; IDA:BHF-UCL.
 GO:0008307; F:structural constituent of muscle; IEA:Compara.
 GO:0007512; P:adult heart development; IEP:BHF-UCL.
 GO:0060048; P:cardiac muscle contraction; IEA:Compara.
 GO:0048739; P:cardiac muscle fiber development; IEA:Compara.
 GO:0014898; P:cardiac muscle hypertrophy in response to stress; IEA:Compara.
 GO:0055008; P:cardiac muscle tissue morphogenesis; IEA:Compara.
 GO:0055003; P:cardiac myofibril assembly; IEA:Compara.
 GO:0035995; P:detection of muscle stretch; IEA:Compara.
 GO:0030916; P:otic vesicle formation; IEP:BHF-UCL.
 GO:0045214; P:sarcomere organization; ISA:MGI.
 GO:0048769; P:sarcomerogenesis; IEA:Compara.
 GO:0003009; P:skeletal muscle contraction; IEA:Compara.
 GO:0030241; P:skeletal muscle myosin thick filament assembly; IEA:Compara.
 GO:0030240; P:skeletal muscle thin filament assembly; IEA:Compara.
 GO:0001756; P:somitogenesis; IEP:BHF-UCL. 
Interpro
 IPR015667; Telethonin.
 IPR023111; Titin-like_domain. 
Pfam
 PF09470; Telethonin 
SMART
  
PROSITE
  
PRINTS