CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041497
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Bromodomain adjacent to zinc finger domain protein 1B 
Protein Synonyms/Alias
 Protein Baz1b 
Gene Name
 Baz1b 
Gene Synonyms/Alias
 rCG_21415 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
407LKAKGRGKGILNGQKacetylation[1]
1328DELVLQTKRSSRRQSacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Bromodomain; Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1476 AA 
Protein Sequence
MAPLLGRKPF PLVKPLPGEE PLFTIPHTQE AFRTREEYEA RLERYSERIW TCKSTGSSQL 60
THKEAWEEEQ EVAELLKEEF PNWYEKLVLE MVHHNTASLE KLVDSAWLEI MTKYAVGEEC 120
DFEVGKEKML KVKIVKIHPL EKVDEEAAEK KSDGTCDSPS SDKENSSQMA QDHQKETVVK 180
EDGGRRESIN DRARRSPRKL PTSLKKGERK WAPPKFLPHK YDVKLQSEDK IISNVPADSL 240
IRTERPPNKE ILRYFIRHNA LRAGTGENAP WVVEDELVKK YSLPSKFSDF LLDPYKYMTL 300
NPSTKRKNTG SPDRKPSKKP KRDNSSLSSP LNPKLWCHVH LEKSLNGPPL KVKNSKNSKS 360
PEEHLEEVMK IMSPNKLHSF HIPKKGPSTK KPGKHSDKPL KAKGRGKGIL NGQKSTGNSK 420
SPSKCVKTPK TKMKQMTLLD MAKGTQKMTR TPRSSGGVPR SSGKPHKHLP PAALHLIAYY 480
KENKDKEDKK SALSCVISKT ARLLSSEDRA RLPEELRALV QKRYELLEHK KRWASMSEEQ 540
RKEYLKKKRQ ELKERLREKA KERREKEMLE RLEKQKRYED QELGGRNLPT FRLVDTPEGL 600
PNTLFGDVAL VVEFLSCYSG LLLPDAQYPI TAVSLMEALS ADKGGFLYLN RVLVILLQTL 660
LQDEIAEDYG ELGMKLSEIP LTLHSVSELV RLCLRRCDVQ EDSEGSDTDD NKDSTPFEDN 720
EVQDEFLEKL ETSEFFELTS EEKLRILTAL CHRILMTYSV QDHMETRQQM SAELWKERLA 780
VLKEENDKKR AEKQKRKEME ARNKENGKEE NVLGKVDRKK EIVKIENQVE VEADDMISAV 840
KSRRLLSMQA KRKREIQERE TKVRLEREAE EERVRKHKAA AEKAFQEGIA KAKLVLRRTP 900
IGTDRNHNRY WLFSNEVPGL FIEKGWVHNS IDYRFKHHRK DHNNLPDDDY CPRSKKANLG 960
KNASVNAHLG SALEAVETTV PKQGQNLWFL CDSQKELDEL LNCLHPQGIR ESQLKERLEK 1020
RYQEITHSIH LARKPNLGLK SCDGNQELLN FLRSDLIEVA TRLQKGGLGY MEGTSEFEAR 1080
VISLEKLKDF GECVIALQAS VIKKFLQGFM APKQKKRKLQ SEDSTKSEEV DEEKKMVEEA 1140
KVASALEKWK TAIREAQTFS RMHVLLGMLD ACIKWDMSAE NARCKVCRKK GEDDKLILCD 1200
ECNKAFHLFC LRPALYEVPD GEWQCPACQP PTARRNSRGR NYTEESTSED SEGDESGDEE 1260
EEEEEEEEEE EDYEVAGLRL RPRKTIRGKQ SVIPAARPGR PPGKKSHAAR RSRPKDDTEV 1320
DELVLQTKRS SRRQSLELQK CEEILHKLVK YRFSWPFREP VTRDEAEDYY DVIDHPMDFQ 1380
TMQNKCSCGN YRSVQEFLTD VKQVFANAEL YNCRGSHVLS CMEKTEQCLL ALLQKHLPGH 1440
PYVRRKRRKF PDRLADDEGD SDSESVGQSR GRRQKK 1476 
Gene Ontology
 GO:0005721; C:centromeric heterochromatin; IEA:Compara.
 GO:0000793; C:condensed chromosome; IEA:Compara.
 GO:0043596; C:nuclear replication fork; IEA:Compara.
 GO:0071778; C:WINAC complex; IEA:Compara.
 GO:0003682; F:chromatin binding; IEA:Compara.
 GO:0035173; F:histone kinase activity; IEA:Compara.
 GO:0004713; F:protein tyrosine kinase activity; IEA:Compara.
 GO:0071884; F:vitamin D receptor activator activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0043044; P:ATP-dependent chromatin remodeling; IEA:Compara.
 GO:0048096; P:chromatin-mediated maintenance of transcription; IEA:Compara.
 GO:0034725; P:DNA replication-dependent nucleosome disassembly; IEA:Compara.
 GO:0006302; P:double-strand break repair; IEA:Compara.
 GO:0003007; P:heart morphogenesis; IEA:Compara. 
Interpro
 IPR001487; Bromodomain.
 IPR018359; Bromodomain_CS.
 IPR018500; DDT_dom_subgr.
 IPR018501; DDT_dom_superfamily.
 IPR013136; WSTF_Acf1_Cbp146.
 IPR019786; Zinc_finger_PHD-type_CS.
 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR019787; Znf_PHD-finger.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF00439; Bromodomain
 PF00628; PHD
 PF10537; WAC_Acf1_DNA_bd 
SMART
 SM00297; BROMO
 SM00571; DDT
 SM00249; PHD
 SM00184; RING 
PROSITE
 PS00633; BROMODOMAIN_1
 PS50014; BROMODOMAIN_2
 PS50827; DDT
 PS51136; WAC
 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2
 PS50089; ZF_RING_2 
PRINTS
 PR00503; BROMODOMAIN.