CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-017074
UniProt Accession
KLD8B_HUMAN
;
Q8IXV7
Genbank Protein ID
AY129011
;
BC039083
Genbank Nucleotide ID
AAM98754.1
;
AAH39083.1
Protein Name
Kelch domain-containing protein 8B
Protein Synonyms/Alias
Gene Name
KLHDC8B
Gene Synonyms/Alias
FP17659
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
186
VLGGRQG
K
LPVTAFE
ubiquitination
[1]
Reference
[1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
Mol Cell. 2011 Oct 21;44(2):325-40. [
PMID: 21906983
]
Functional Description
Sequence Annotation
REPEAT 1 31 Kelch 1.
REPEAT 32 79 Kelch 2.
REPEAT 81 127 Kelch 3.
REPEAT 128 175 Kelch 4.
REPEAT 176 222 Kelch 5.
REPEAT 224 281 Kelch 6.
REPEAT 282 329 Kelch 7.
REPEAT 331 354 Kelch 8.
Keyword
Chromosomal rearrangement; Complete proteome; Cytoplasm; Kelch repeat; Reference proteome; Repeat.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
354 AA
Protein Sequence
MSAGGGRAFA WQVFPPMPTC RVYGTVAHQD GHLLVLGGCG RAGLPLDTAE TLDMASHTWL 60
ALAPLPTARA GAAAVVLGKQ VLVVGGVDEV QSPVAAVEAF LMDEGRWERR ATLPQAAMGV 120
ATVERDGMVY ALGGMGPDTA PQAQVRVYEP RRDCWLSLPS MPTPCYGAST FLHGNKIYVL 180
GGRQGKLPVT AFEAFDLEAR TWTRHPSLPS RRAFAGCAMA EGSVFSLGGL QQPGPHNFYS 240
RPHFVNTVEM FDLEHGSWTK LPRSLRMRDK RADFVVGSLG GHIVAIGGLG NQPCPLGSVE 300
SFSLARRRWE ALPAMPTARC SCSSLQAGPR LFVIGGVAQG PSQAVEALCL RDGV 354
Gene Ontology
GO:0005737
; C:cytoplasm; IDA:HPA.
Interpro
IPR015915
; Kelch-typ_b-propeller.
IPR006652
; Kelch_1.
Pfam
PF01344
; Kelch_1
SMART
SM00612
; Kelch
PROSITE
PRINTS