CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039750
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 GPI transamidase component PIG-S 
Protein Synonyms/Alias
  
Gene Name
 PIGS 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
34HEREIPLKYKMKIKCubiquitination[1]
397KISNIVIKDDVASEVubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 494 AA 
Protein Sequence
MVPVTVVFTR ESVPLDDQEK LPFTVVHERE IPLKYKMKIK CRFQKAYRRA LDHEEEALSS 60
GSVQEAEAML DEPQEQAEGS LTVYVISEHS SLLPQDMMSY IGPKRTAVVR GIMHREAFNI 120
IGRRIVQVAQ AMSLTEDVLA AALADHLPED KWSAEKRRPL KSSLGYEITF SLLNPDPKSH 180
DVYWDIEGAV RRYVQPFLNA LGAAGNFSVD SQILYYAMLG VNPRFDSASS SYYLDMHSLP 240
HVINPVESRL GSSAASLYPV LNFLLYVPEL AHSPLYIQDK DGAPVATNAF HSPRWGGIMV 300
YNVDSKTYNA SVLPVRVEVD MVRVMEVFLA QLRLLFGIAQ PQLPPKCLLS GPTSEGLMTW 360
ELDRLLWARS VENLATATTT LTSLAQLLGK ISNIVIKDDV ASEVYKAVAA VQKSAEELAS 420
GHLASAFVAS QEAVTSSELA FFDPSLLHLL YFPDDQKFAI YIPLFLPMAV PILLSLVKIF 480
LETRKSWRKP EKTD 494 
Gene Ontology
 GO:0042765; C:GPI-anchor transamidase complex; IEA:InterPro.
 GO:0003923; F:GPI-anchor transamidase activity; IEA:Compara.
 GO:0016255; P:attachment of GPI anchor to protein; IEA:InterPro. 
Interpro
 IPR019540; PtdIno-glycan_biosynth_class_S. 
Pfam
 PF10510; PIG-S 
SMART
  
PROSITE
  
PRINTS