CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037154
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Autophagy-related protein 16-1 
Protein Synonyms/Alias
  
Gene Name
 ATG16L1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
530CSRDDLLKVIDLRTNubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 624 AA 
Protein Sequence
MSSGLRAADF PRWKRHISEQ LRRRDRLQRQ AFEEIILQYN KLLEKSDLHS VLAQKLQAEK 60
HDVPNRHEIS PGHDGTWNDN QLQEMAQLRI KHQEELTELH KKRGELAQLV IDLNNQMQRK 120
DREMQMNEAK IAECLQTISD LETECLDLRT KLCDLERANQ TLKDEYDALQ ITFTALEGKL 180
RKTTEENQEL VTRWMAEKAQ EANRLNAENE KDSRRRQARL QKELAEAAKE PLPVEQDDDI 240
EVIVDETSDH TEETSPVRAI SRAATKRLSQ PAGGLLDSIT NIFGLSESPL LGHHSSSDAA 300
RRRSVSSFPV PQDNVDTHPG SGKEVRVPAT ALCVFDAHDG EVNAVQFSPG SRLLATGGMD 360
RRVKLWEVFG EKCEFKGSLS GSNAGITSIE FDSAGSYLLA ASNDFASRIW TVDDYRLRHT 420
LTGHSGKVLS AKFLLDNARI VSGSHDRTLK LWDLRSKVCI KTVFAGSSCN DIVCTEQCVM 480
SGHFDKKIRF WDIRSESIVR EMELLGKITA LDLNPERTEL LSCSRDDLLK VIDLRTNAIK 540
QTFSAPGFKC GSDWTRVVFS PDGSYVAAGS AEGSLYIWSV LTGKVEKVLS KQHSSSINAV 600
AWSPSGSHVV SVDKGCKAVL WAQY 624 
Gene Ontology
  
Interpro
 IPR013923; Autophagy-rel_prot_16.
 IPR020472; G-protein_beta_WD-40_rep.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF08614; ATG16
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.