CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028871
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 HLA class II histocompatibility antigen, DQ beta 1 chain 
Protein Synonyms/Alias
  
Gene Name
 HLA-DQB1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
257IIHHRSQKGLLH***ubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Immunity; Membrane; MHC II; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 261 AA 
Protein Sequence
MSWKKALRIP GGLRVATVTL MLAMLSTPVA EGRDSPEDFV YQFKGMCYFT NGTERVRGVT 60
RYIYNREEYA RFDSDVGVYR AVTPLGPPAA EYWNSQKEVL ERTRAELDTV CRHNYQLELR 120
TTLQRRVEPT VTISPSRTEA LNHHNLLVCS VTDFYPAQIK VRWFRNDQEE TTGVVSTPLI 180
RNGDWTFQIL VMLEMTPQRG DVYTCHVEHP SLQNPIIVEW RAQSESAQSK MLSGIGGFVL 240
GLIFLGLGLI IHHRSQKGLL H 261 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW.
 GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW.
 GO:0006955; P:immune response; IEA:InterPro. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003006; Ig/MHC_CS.
 IPR003597; Ig_C1-set.
 IPR011162; MHC_I/II-like_Ag-recog.
 IPR014745; MHC_II_a/b_N.
 IPR000353; MHC_II_b_N. 
Pfam
 PF07654; C1-set
 PF00969; MHC_II_beta 
SMART
 SM00407; IGc1
 SM00921; MHC_II_beta 
PROSITE
 PS50835; IG_LIKE
 PS00290; IG_MHC 
PRINTS