UniProt Accession

 T185B_HUMAN; Q9H7F4; A8K1G5; Q53T33; Q66K44; Q8IZ77 

Genbank Protein ID

 AK024632; AK289880; AC012363; BC016849; BC080607 

Genbank Nucleotide ID

 BAB14938.1; BAF82569.1; AAY14799.1 

Protein Name

 Putative transmembrane protein 185B 

Protein Synonyms/Alias

 Protein FAM11B 

Gene Name

 TMEM185B 

Gene Synonyms/Alias

 FAM11B 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
325	IAPIFGKKARVVITQ	ubiquitination	[1]
336	VITQSPGKYVPPPPK	ubiquitination	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 350 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 

Interpro

 IPR019396; TM_Fragile-X-F-assoc. 

Pfam

 PF10269; Tmemb_185A 

SMART

  

PROSITE

  

PRINTS