UniProt Accession

 TATD3_HUMAN; Q17R31; A6NGS3; B7Z1C1; B7Z978; B7ZLQ6; E9PJE5; E9PNH3; G3V151; Q4G0L1 

Genbank Protein ID

 AK293129; AK304557; AC104333; CH471100; CH471100; CH471100; BC048115; BC113638; BC117485; BC143956 

Genbank Nucleotide ID

 BAH11457.1; BAH14214.1; EAW93376.1; EAW93377.1; EAW93378.1; AAH48115.1; AAI13639.1; AAI17486.1; AAI43957.1 

Protein Name

 Putative deoxyribonuclease TATDN3 

Protein Synonyms/Alias

  

Gene Name

 TATDN3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
86	DQRSVTLKDLDVALP	ubiquitination	[1]
99	LPIIENYKDRLLAIG	ubiquitination	[1]
123	FAGTGEQKEEQRQVL	ubiquitination	[1]
226	SPALGPEKQVRNEPW	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Putative deoxyribonuclease. 

Sequence Annotation

 METAL 12 12 Divalent metal cation 1.
 METAL 14 14 Divalent metal cation 1.
 METAL 107 107 Divalent metal cation 1.
 METAL 107 107 Divalent metal cation 2.
 METAL 147 147 Divalent metal cation 2.
 METAL 170 170 Divalent metal cation 2.
 METAL 218 218 Divalent metal cation 1.  

Keyword

 3D-structure; Alternative splicing; Complete proteome; Hydrolase; Metal-binding; Nuclease; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 274 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. 

Interpro

 IPR001130; TatD_family. 

Pfam

 PF01026; TatD_DNase 

SMART

  

PROSITE

 PS01090; TATD_2
 PS01091; TATD_3 

PRINTS