CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029429
UniProt Accession
Genbank Protein ID
 L29074 
Genbank Nucleotide ID
  
Protein Name
 Fragile X mental retardation protein 1 
Protein Synonyms/Alias
  
Gene Name
 FMR1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
74VYSRANEKEPCCWWLubiquitination[1]
295VPRNLVGKVIGKNGKubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 582 AA 
Protein Sequence
MEELVVEVRG SNGAFYKAFV KDVHEDSITV AFENNWQPDR QIPFHDVRFP PPVGYNKDIN 60
ESDEVEVYSR ANEKEPCCWW LAKVRMIKGE FYVIEYAACD ATYNEIVTIE RLRSVNPNKP 120
ATKDTFHKIK LDVPEDLRQM CAKEAAHKDF KKAVGAFSVT YDPENYQLVI LSINEVTSKR 180
AHMLIDMHFR SLRTKLSLIM RNEEASKQLE SSRQLASRFH EQFIVREDLM GLAIGTHGAN 240
IQQARKVPGV TAIDLDEDTC TFHIYGEDQD AVKKARSFLE FAEDVIQVPR NLVGKVIGKN 300
GKLIQEIVDK SGVVRVRIEA ENEKNVPQEE EIMPPNSLPS NNSRVGPNAP EEKKHLDIKE 360
NSTHFSQPNS TKVQRGMVPF VFVGTKDSIA NATVLLDYHL NYLKEVDQLR LERLQIDEQL 420
RQIGASSRPP PNRTDKEKSY VTDDGQGMGR GSRPYRNRGH GRRGPGYTSE SDHRDELSDW 480
SLAPTEEERE SFLRRGDGRR RGGGGRGQGG RGRGGGFKGN DDHSRTDNRP RNPREAKGRT 540
TDGSLQNTSS EGSRLRTGKD RNQKKEKPDS VDGQQPLVNG VP 582 
Gene Ontology
 GO:0003723; F:RNA binding; IEA:InterPro. 
Interpro
 IPR008395; Agenet-like_dom.
 IPR022034; Frag_X_MRP_fam.
 IPR004087; KH_dom.
 IPR004088; KH_dom_type_1. 
Pfam
 PF05641; Agenet
 PF12235; FXR1P_C
 PF00013; KH_1 
SMART
 SM00322; KH 
PROSITE
 PS51641; AGENET_LIKE
 PS50084; KH_TYPE_1 
PRINTS